SureCN6783582 (CID 9821494) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Unspecified(4)
 
 
BioAssay Types:
Literature(4)
 
 
BioActivity Types:
IC50(1)
 
 
SAR
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103404956]
IC50 32Cytotoxicity against MCF-7 breast carcinoma cells at 10 ug/mL [AID103349, Type: Literature]
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2
[SID103404956]
 Ratio for antagonistic activity for Pgp/MRP1 was determined [AID231934, Type: Literature]
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3
[SID103404956]
 The P-glycoprotein (Pgp) antagonism score is the percentage of NCI/ADR cells surviving in the absence of vinblastine to that of in the presence of vinblastine. [AID230144, Type: Literature]
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4
[SID103404956]
 The MRP1 antagonism score is the percentage of MCF-7/VP cells surviving in the absence of vincristine to that of in the presence of vincristine. [AID230143, Type: Literature]
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