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Phencyclidine (CID 9795678) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(372)
 
 
Unspecified(8)
 
 
Top Targets:
7tm 4(33)
 
 
 
Peptidase C48(4)
 
 
Troponin(4)
 
 
CAP ED(4)
 
 
RasGEF(4)
 
 
BioAssay Types:
Screening(267)
 
 
 
Confirmatory(99)
 
 
 
 
Literature(19)
 
 
 
 
BioActivity Types:
Potency(85)
 
 
 
IC50(8)
 
 
 
EC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 347    Data Row: 388   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103670245]
IC50 0.27Inhibitory concentration for [3H]PCP binding to rat brain homogenate relative to PCP [AID195553, Type: Literature]
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2
[SID85273813]
EC50 0.961Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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3
[SID85273813]
EC50 0.961Luminescence-based cell-based high throughput dose response assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID588407, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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4
[SID85273813]
EC50 6.29Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRM1 homodimerization [AID588435, Type: confirmatory]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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5
[SID85273813]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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6
[SID85273813]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504326, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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7
[SID85273813]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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8
[SID85273813]
Luminescence-based cell-based high throughput confirmation assay for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors [AID504904, Type: screening]mu-type opioid receptor isoform MOR-1 [Homo sapiens] [gi:117940060]
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9
[SID103670245]
Half-life determined in the urine of dog [AID23795, Type: Literature]
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10
[SID103670245]
Half-life determined in the urine of monkey [AID23796, Type: Literature]
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11
[SID103670245]
Compound was evaluated for the mean locomotor activity (GABA-ergic agonism) by the difference in the counts between postinjection and preinjection activities. [AID57330, Type: Literature]
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12
[SID103670245]
Tested for its effect on Hypoxia induced neuronal damage [AID74940, Type: Literature]
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13
[SID103670245]
Tested for its effect on hippocampal neuronal damage in gerbils activity [AID74941, Type: Literature]
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14
[SID103670245]
Relative potency in the rat discriminative stimulus assay, expressed as mg of PCP (= 1.0 mg of compound) [AID187492, Type: Literature]
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15
[SID103670245]
Ability to displace 7.0 nM [3H]PCP binding to rat brain homogenate relative to PCP (IC50= 270 nM) [AID195690, Type: Literature]
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16
[SID85273813]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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17
[SID85273813]
EC50 33.637Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization [AID588411, Type: confirmatory]delta-type opioid receptor [Homo sapiens] [gi:63477962]
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18
[SID85273813]
Potency 79.4328HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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19
[SID85273813]
EC50 92.517Counterscreen for agonists of OPRM1-OPRD1 heterodimerization: luminescence-based cell-based high throughput dose response assay to identify agonists of 5-hydroxytryptamine (serotonin) 5A receptor (HTR5A) [AID588408, Type: confirmatory]5-hydroxytryptamine receptor 5A [Homo sapiens] [gi:13236497]
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20
[SID85273813]
Potency 100qHTS for Inhibitors of Polymerase Iota [AID588590, Type: confirmatory]DNA polymerase iota [Homo sapiens] [gi:154350220]
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