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BioActivity Data for Compound Oxaloacetic Acid (CID 970)

BioActivity Outcomes:
Active(5)
 
 
Inactive(99)
 
 
Inconclusive(3)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
NR LBD GR(4)
 
 
BioAssay Types:
Confirmatory(72)
 
 
 
Summary(29)
 
 
 
Literature(5)
 
 
BioAssay Categories:
Toxicity(6)
 
 
BioActivity Types:
Potency(95)
 
 
 
Kd(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 107   Total Pages: 6   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID46394380]
Kd 10Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crystal Structure Analysis And Molecular Model Of A Complex Of Citrate Synthase With Oxaloacetate And S-Acetonyl- Coenzyme A [gi:230994]
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2
[SID46394380]
Kd 10Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain B, Crystal Structure Analysis And Molecular Model Of A Complex Of Citrate Synthase With Oxaloacetate And S-Acetonyl- Coenzyme A [gi:230994]
View
3
[SID46394380]
Kd 10Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Analysis And Molecular Model Of A Complex Of Citrate Synthase With Oxaloacetate And S-Acetonyl- Coenzyme A [gi:230993]
View
4
[SID46394380]
Kd 10Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]Chain A, Crystal Structure Analysis And Molecular Model Of A Complex Of Citrate Synthase With Oxaloacetate And S-Acetonyl- Coenzyme A [gi:230993]
View
5
[SID46394380]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Analysis And Molecular Model Of A Complex Of Citrate Synthase With Oxaloacetate And S-Acetonyl- Coenzyme A [gi:230993]
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6
[SID144208413]
Ratio Potency (uM) qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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7
[SID144208413]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway [AID743210, Type: confirmatory]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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8
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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9
[SID144208413]
Antagonist Potency (uM) qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway: Summary [AID1159523, Type: summary]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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10
[SID144208413]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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11
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the NFkB signaling pathway - cell viability counter screen [AID1159515, Type: confirmatory]
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12
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the endoplasmic reticulum stress response signaling pathway - cell viability counter screen [AID1159517, Type: confirmatory]
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13
[SID144208413]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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14
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway - cell viability counter screen [AID1159525, Type: confirmatory]
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15
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the AP-1 signaling pathway [AID1159526, Type: confirmatory]
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16
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the RXR signaling pathway - cell viability counter screen [AID1159529, Type: confirmatory]
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17
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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18
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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19
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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20
[SID144208413]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID1159520, Type: confirmatory]
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