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Curcumin (CID 969516) - Compound BioActivity Data
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BioActivity Outcomes:
Active(419)
 
 
Inactive(1019)
 
 
Inconclusive(335)
 
 
Unspecified(11)
 
 
Top Targets:
7tm 4(56)
 
 
 
NR LBD ER(26)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD PPAR(23)
 
 
 
 
alkPPc(20)
 
 
 
BioAssay Types:
Confirmatory(745)
 
 
 
 
 
Screening(678)
 
 
 
 
 
Literature(89)
 
 
 
 
 
Summary(54)
 
 
 
 
BioActivity Types:
Potency(588)
 
 
 
 
 
IC50(62)
 
 
 
 
EC50(13)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1193    Data Row: 1784   Total Pages: 90   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144208314]
Potency-Replicate_1 0.5482qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144204354]
Potency-Replicate_1 0.7498qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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3
[SID144204354]
Ratio Potency (uM) 0.90838qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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4
[SID144208314]
Ratio Potency (uM) 1.15851qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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5
[SID144205058]
Potency-Replicate_1 1.6785qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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6
[SID144205058]
Ratio Potency (uM) 2.40651qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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7
[SID56422380]
AbsAC35_uM 2.54Luminescence cell-based Retest at Dose assay to determine EWS/Fli1 dependent A673 mammalian cell cytotoxity Measured in Cell-Based System Using Plate Reader - 7014-03_Inhibitor_Dose_CherryPick_Activity [AID720587, Type: confirmatory]
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8
[SID855880]
Potency 2.5929qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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9
[SID17389087]
Potency 3.1623qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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10
[SID17389087]
Potency 3.1623qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
View
11
[SID50104137]
Potency 3.5481qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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12
[SID855880]
Potency 3.5481qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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13
[SID17389087]
Potency 3.7578qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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14
[SID17389087]
Potency 3.9811qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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15
[SID17389087]
Potency 3.9811qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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16
[SID17389087]
Potency 5.9557qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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17
[SID855880]
EC50 6.97Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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18
[SID855880]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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19
[SID855880]
IC50 7.751Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) [AID588341, Type: confirmatory]Beta lactamase [Pseudomonas aeruginosa] [gi:114881106]
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20
[SID56422380]
AbsAC35_uM 7.91Luminescence Cell-Based Primary HTS to identify inhibitors of the oncoprotein EWS/Fli transcriptional activity Measured in Cell-Based System Using Plate Reader - 7014-01_Inhibitor_Dose_CherryPick_Activity [AID686920, Type: confirmatory]
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