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T0510-0863 (CID 9668037) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(250)
 
 
Inconclusive(6)
 
 
Top Targets:
7TM GPCR Srx(9)
 
 
Bcl-2 like(8)
 
 
G-alpha(6)
 
 
 
alkPPc(6)
 
 
7TM GPCR Srsx(6)
 
 
BioAssay Types:
Screening(128)
 
 
 
 
Confirmatory(123)
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(71)
 
 
 
 
IC50(30)
 
 
EC50(17)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 240    Data Row: 262   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24791718]
Potency 50.1187qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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2
[SID24791718]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype [AID757, Type: screening]Rac1 protein [Homo sapiens] [gi:8574038]
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3
[SID24791718]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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4
[SID24791718]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype [AID758, Type: screening]GTP-binding protein (rab7) [Canis lupus familiaris] [gi:164058]
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5
[SID24791718]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype [AID760, Type: screening]Ras-related protein Rab-2A [gi:46577642]
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6
[SID24791718]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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7
[SID24791718]
EC50_MICROM Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant [AID1341, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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8
[SID24791718]
EC50_MICROM Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID1335, Type: confirmatory]ras protein, partial [Homo sapiens] [gi:190938]
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9
[SID24791718]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2. [AID950, Type: screening]Apoptosis regulator Bcl-2 [gi:231632]
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10
[SID24791718]
Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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11
[SID24791718]
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation [AID1285, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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12
[SID24791718]
Thrombin 1536 HTS [AID1046, Type: screening]prothrombin [Homo sapiens] [gi:339641]
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13
[SID24791718]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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14
[SID24791718]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1007, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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15
[SID24791718]
Potency qHTS Assay for Inhibitors of Human alpha-Galactosidase at pH 4.5. [AID1467, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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16
[SID24791718]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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17
[SID24791718]
Multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. [AID1439, Type: screening]RGS7, partial [Homo sapiens] [gi:1166512]
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18
[SID24791718]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. [AID952, Type: screening]Bcl-w [Homo sapiens] [gi:1572493]
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19
[SID24791718]
uHTS for Calpain Inhibitors [AID1236, Type: screening]calpain II, partial [Sus scrofa] [gi:1628587]
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20
[SID24791718]
Potency Counterscreen for Luciferase (Kinase-Glo TM) Inhibition [AID1379, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
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