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MLS000724462 (CID 9653891) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(686)
 
 
Inconclusive(7)
 
 
Unspecified(6)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(17)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(477)
 
 
 
 
Confirmatory(195)
 
 
 
 
Literature(16)
 
 
 
BioActivity Types:
Potency(142)
 
 
 
 
IC50(40)
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 635    Data Row: 701   Total Pages: 36   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24810136]
Aqueous Solubility from MLSMR Stock Solutions [AID1996, Type: other]
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2
[SID24810136]
HTS to identify compounds that promote myeloid differentiation with MLPCN compound set [AID624256, Type: screening] [geneid:3205]
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3
[SID174496118]
IC50 58.3Inhibition of Escherichia coli N-terminal His-tagged full length FabH expressed in Escherichia coli BL21 (DE3) using [3H]acetyl-CoA as substrate assessed as incorporation of [3H] signal into product after 25 mins by liquid scintillation counting analysis [AID749374, Type: Literature]
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4
[SID174496118]
Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by two fold serial dilution method [AID749375, Type: Literature]
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5
[SID174496118]
Antimicrobial activity against Bacillus subtilis ATCC 530 after 24 hrs by two fold serial dilution method [AID749376, Type: Literature]
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6
[SID174496118]
Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by two fold serial dilution method [AID749377, Type: Literature]
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7
[SID174496118]
Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by two fold serial dilution method [AID749378, Type: Literature]
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8
[SID24810136]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID24810136]
Factor XIa 1536 HTS [AID798, Type: screening]coagulation factor XI [Homo sapiens] [gi:180352]
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10
[SID24810136]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype [AID759, Type: screening]ras protein, partial [Homo sapiens] [gi:190938]
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11
[SID24810136]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2. [AID950, Type: screening]Apoptosis regulator Bcl-2 [gi:231632]
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12
[SID24810136]
Primary screen for compounds that activate Alzheimer's amyloid precursor [AID1276, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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13
[SID24810136]
Primary screen for compounds that inhibit Alzheimer's amyloid precursor protein (APP) translation [AID1285, Type: screening]amyloid precursor protein [Homo sapiens] [gi:257380]
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14
[SID24810136]
Thrombin 1536 HTS [AID1046, Type: screening]prothrombin [Homo sapiens] [gi:339641]
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15
[SID24810136]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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16
[SID24810136]
Primary cell-based high-throughput screening assay for identification of compounds that protect hERG from block by proarrhythmic agents [AID1511, Type: screening]putative potassium channel subunit [Homo sapiens] [gi:487738]
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17
[SID24810136]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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18
[SID24810136]
Primary biochemical high throughput screening assay to identify inhibitors of BCL2-related protein, long isoform (BCLXL). [AID2129, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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19
[SID24810136]
Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. [AID1007, Type: screening]bcl-xL [Homo sapiens] [gi:510901]
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20
[SID24810136]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ RPL19A_MLPCN. [AID2025, Type: screening]RPL19A [Saccharomyces cerevisiae] [gi:536029]
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