1-Propyl theobromine (CID 96448) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(6)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srsx(1)
 
 
BioAssay Types:
Literature(3)
 
 
 
BioActivity Types:
Ki(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 9   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103193796]
Ki 5Compound was evaluated for its ability to antagonise cyclic [3H]AMP accumulation in [3H]adenine-labeled guinea pig cerebral cortical slices. [AID30626, Type: Literature]Adenosine receptor A2 [gi:1168253]
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2
[SID103193796]
Ki 38Ability to inhibit binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptor in rat cerebral cortical membranes [AID31714, Type: Literature]
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3
[SID103193796]
 Selectivity was expressed as the ratio is Ki of adenosine A1 receptor to that of adenosine A2 receptor [AID233904, Type: Literature]
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4
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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5
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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6
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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7
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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8
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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9
[SID116571]
 NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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