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BioActivity Data for Compound STK143941 (CID 9587374)

BioActivity Outcomes:
Active(35)
 
 
Inactive(721)
 
 
Inconclusive(16)
 
 
Unspecified(9)
 
 
Top Targets:
7tm 4(43)
 
 
 
Bcl-2 like(17)
 
 
 
alkPPc(12)
 
 
TNFRSF10(12)
 
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(525)
 
 
 
 
 
Confirmatory(231)
 
 
 
 
 
Literature(11)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(123)
 
 
 
Toxicity(9)
 
 
 
Cell-based(141)
 
 
 
 
Organism-base..(13)
 
 
 
 
BioActivity Types:
Potency(148)
 
 
 
 
 
IC50(47)
 
 
EC50(26)
 
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 705    Data Row: 781   Total Pages: 40   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17415033]
EC50 0.376Fluorescence Cell-Based Retest of C. albicans Growth in the Presence of Fluconazole [AID2467, Type: confirmatory]
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2
[SID17415033]
EC50 0.893Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole [AID2423, Type: confirmatory]heat shock protein 90 [Candida albicans] [gi:994798]
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3
[SID17415033]
AC50_uM 2.218Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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4
[SID17415033]
AC50_uM 3.012HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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5
[SID17415033]
EC50_MICROM 5.045Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits [AID2745, Type: confirmatory]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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6
[SID17415033]
EC50_MICROM 10.35Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically CIT2 based on MLPCN hits [AID2744, Type: confirmatory]citrate synthase 2, partial [Saccharomyces cerevisiae] [gi:171229]
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7
[SID17415033]
Potency 10.691Tb PFK orthogonal confirmatory assay using ATP depletion (Kinase-Glo Plus) as an alternative measure of Tb PFK activity: Hit Validation [AID504636, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:72386991]
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8
[SID17415033]
EC50 11.631Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90 [AID2400, Type: confirmatory]heat shock protein 90 [Candida albicans] [gi:994798]
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9
[SID17415033]
Screening for Modulators of Post-Golgi Transport, Control Strain [AID738, Type: screening]
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10
[SID17415033]
Luminescence Microorganism Primary HTS to Identify Inhibitors of the SUMOylation Pathway Using a Temperature Sensitive Growth Reversal Mutant Mot1-301 [AID2716, Type: screening]
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11
[SID17415033]
Screen for Chemicals that Shorten Yeast Lifespan [AID804, Type: screening]
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12
[SID17415033]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically CIT2 Cherry Pick Compounds [AID2274, Type: screening]citrate synthase 2, partial [Saccharomyces cerevisiae] [gi:171229]
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13
[SID17415033]
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Potentiators [AID624464, Type: other]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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14
[SID17415033]
Beta-Arrestin HTS for Positive Allosteric Modulators of the Human D2 Dopamine Receptor: Antagonists [AID624463, Type: other]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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15
[SID17415033]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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16
[SID17415033]
Single concentration confirmation of uHTS hits from a small molecule agonists of the APJ receptor via a luminescent beta-arrestin assay [AID2764, Type: screening]apelin receptor [Homo sapiens] [gi:4885057]
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17
[SID17415033]
uHTS identification of small molecule agonists of the APJ receptor via a luminescent beta-arrestin assay [AID2520, Type: screening]apelin receptor [Homo sapiens] [gi:4885057]
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18
[SID17415033]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae, specifically LAP4 Cherry Pick Compounds [AID2271, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
View
19
[SID17415033]
Multiplex HTS Screen of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae_specifically_ LAP4_MLPCN. [AID2023, Type: screening]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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20
[SID17415033]
Luminescence-based cell-based primary high throughput screening assay to identify biased ligands of the melanocortin 4 receptor (MC4R): agonists of MC4R [AID540308, Type: screening]melanocortin receptor 4 [Homo sapiens] [gi:119508433]
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