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nifursol (CID 9570327) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(35)
 
 
Inactive(102)
 
 
Inconclusive(54)
 
 
Unspecified(133)
 
 
Top Targets:
7tm 4(33)
 
 
 
p450(10)
 
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD PPAR(8)
 
 
NR LBD AR(8)
 
 
 
BioAssay Types:
Confirmatory(215)
 
 
 
 
 
Literature(66)
 
 
 
 
 
Summary(24)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(116)
 
 
 
 
IC50(116)
 
 
 
EC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 261    Data Row: 324   Total Pages: 17   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170466422]
Ratio Potency (uM) 2.9847qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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2
[SID103646320]
IC50 5DRUGMATRIX: CYP450, 2C19 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625247, Type: confirmatory]Cytochrome P450 2C19 [gi:60416369]
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3
[SID103646320]
IC50 7DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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4
[SID103646320]
EC50 15Antitrypanosomal activity against Trypanosoma cruzi amastigotes infected in BESM cells measured after 88 hrs postinfection by HTS assay [AID547622, Type: Literature]
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5
[SID144205448]
Potency-Replicate_1 26.6032qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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6
[SID144205448]
Potency-Replicate_1 29.8493qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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7
[SID29216239]
Potency 36.1254Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_46, Type: Literature]
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9
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_48, Type: Literature]
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10
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_49, Type: Literature]
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11
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_52, Type: Literature]
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12
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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13
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_6, Type: Literature]
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14
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
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15
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_8, Type: Literature]
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16
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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17
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_10, Type: Literature]
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18
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_11, Type: Literature]
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19
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_13, Type: Literature]
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20
[SID29216239]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_15, Type: Literature]
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