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Chlorhexidine (CID 9562059) - Compound BioActivity Data
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BioActivity Outcomes:
Active(34)
 
 
Inactive(28)
 
 
Inconclusive(61)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
BioAssay Types:
Confirmatory(91)
 
 
 
 
Summary(24)
 
 
 
 
Literature(4)
 
 
BioActivity Types:
Potency(109)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 120    Data Row: 128   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144212680]
Ratio Potency (uM) 2.15916qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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2
[SID144212680]
Ratio Potency (uM) 3.87186qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway: Summary [AID743063, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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3
[SID144212680]
Potency-Replicate_1 4.3081qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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4
[SID144212680]
Potency-Replicate_1 6.0853qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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5
[SID144212680]
Potency-Replicate_1 7.661qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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6
[SID144212680]
Ratio Potency (uM) 8.34167qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID144212680]
Potency-Replicate_1 10.9124qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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8
[SID144212680]
Potency-Replicate_1 10.9124qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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9
[SID144212680]
Potency-Replicate_1 10.9124qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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10
[SID144212680]
Potency-Replicate_1 13.7379qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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11
[SID144212680]
Potency-Replicate_1 15.2857qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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12
[SID144212680]
Potency-Replicate_1 15.4141qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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13
[SID144212680]
Potency-Replicate_1 15.4141qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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14
[SID144212680]
Potency-Replicate_1 15.4141qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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15
[SID144212680]
Potency-Replicate_1 17.295qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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16
[SID144212680]
Potency-Replicate_1 19.4053qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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17
[SID144212680]
Potency-Replicate_1 19.4053qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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18
[SID144212680]
Potency-Replicate_1 19.4053qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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19
[SID144212680]
Potency-Replicate_1 21.5916qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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20
[SID144212680]
Potency-Replicate_1 21.5916qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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