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MLS000080795 (CID 9557441) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(829)
 
 
Inconclusive(7)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
alkPPc(16)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
BioAssay Types:
Screening(556)
 
 
 
Confirmatory(255)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
IC50(51)
 
 
 
EC50(12)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 769    Data Row: 841   Total Pages: 43   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID856263]
IC50_Artemis_Mean 3.62Dose Response confirmation of small molecule inhibitors originally identified via uHTS of Artemis endonuclease activity via a fluorescence intensity assay [AID720701, Type: confirmatory]protein artemis isoform a [Homo sapiens] [gi:76496497]
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2
[SID856263]
Primary cell-based high-throughput screening for identification of compounds that antagonize MrgX1 receptor signaling [AID588676, Type: screening]MAS-related GPR member X1 [Homo sapiens] [gi:195969650]
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3
[SID856263]
uHTS identification of small molecule inhibitors of Artemis endonuclease activity via a fluorescence intensity assay [AID686954, Type: screening]protein artemis isoform a [Homo sapiens] [gi:76496497]
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4
[SID856263]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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5
[SID856263]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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6
[SID856263]
Potency 50.1187qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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7
[SID856263]
Potency qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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8
[SID856263]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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9
[SID856263]
Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624126, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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10
[SID856263]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624127, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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11
[SID856263]
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen [AID449739, Type: screening]voltage-dependent T-type calcium channel subunit alpha-1H isoform a [Homo sapiens] [gi:53832009]
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12
[SID856263]
HTS-Luminescent assay for inhibitors of ALR by detection of hydrogen peroxide production Measured in Biochemical System Using Plate Reader - 2036-02_Inhibitor_SinglePoint_HTS [AID485317, Type: screening]FAD-linked sulfhydryl oxidase ALR [Homo sapiens] [gi:54112432]
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13
[SID856263]
Primary Cell Based High Throughput Screening Assay for Enhancers of Beta-Glucosidase Activity [AID784, Type: screening]Glucosylceramidase [gi:55584151]
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14
[SID856263]
Primary cell-based high-throughput screening assay for inhibitors of TLR4-MyD88 binding [AID861, Type: screening]toll-like receptor 4 [Homo sapiens] [gi:55662034]
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15
[SID856263]
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) antagonists [AID612, Type: screening]5-hydroxytryptamine receptor 1A [Homo sapiens] [gi:55956923]
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16
[SID856263]
Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) agonists [AID567, Type: screening]5-hydroxytryptamine receptor 1A [Homo sapiens] [gi:55956923]
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17
[SID856263]
QFRET-based counterscreen for PFM18AAP inhibitors: biochemical high throughput screening assay to identify inhibitors of the Cathepsin L proteinase (CTSL1). [AID1906, Type: screening]cathepsin L1 [Homo sapiens] [gi:55958172]
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18
[SID856263]
Counterscreen for procaspase-3 activators: absorbance-based primary biochemical high throughput screening assay to identify activators of procaspase-7 [AID463210, Type: screening]caspase 7, apoptosis-related cysteine peptidase [Homo sapiens] [gi:55960760]
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19
[SID856263]
MLPCN maternal gene expression-MEX-5 TCR-2 binding assay-Primary Screen [AID1832, Type: screening]Zinc finger protein mex-5 [gi:55976631]
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20
[SID856263]
HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype [AID761, Type: screening]cell division cycle 42 (GTP binding protein, 25kDa) [Homo sapiens] [gi:56202836]
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