SMR000130535 (CID 9550906) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(9)
 
 
Inactive(716)
 
 
Inconclusive(13)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(25)
 
 
 
alkPPc(12)
 
 
Bcl-2 like(10)
 
 
7TM GPCR Srsx(8)
 
 
Pyr redox dim(8)
 
 
BioAssay Types:
Screening(469)
 
 
 
 
 
Confirmatory(254)
 
 
 
 
 
Literature(6)
 
 
BioActivity Types:
Potency(194)
 
 
 
 
IC50(41)
 
 
 
 
EC50(9)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 667    Data Row: 741   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103904146]
IC50 1.71A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (5) [AID493088, Type: confirmatory]
View
2
[SID124365630]
IC50 2.5A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) using synthesized compounds (12) [AID540337, Type: confirmatory]
View
3
[SID14737103]
IC50 2.98A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
View
4
[SID124365630]
CC50 69An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (12) [AID540338, Type: confirmatory]
View
5
[SID14737103]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
6
[SID14737103]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
7
[SID14737103]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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8
[SID14737103]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
9
[SID14737103]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
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10
[SID14737103]
 Screen for Chemicals that Inhibit the RAM Network [AID868, Type: screening]
View
11
[SID93616798]
 A Titer Reduction Assay to evaluate Selected Compounds as new Inhibitors of Respiratory Syncytial Virus (RSV) [AID449732, Type: other]
View
12
[SID14737103]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
13
[SID14737103]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
14
[SID14737103]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
15
[SID24269910]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
16
[SID24269910]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
17
[SID24269910]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
18
[SID24269910]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
19
[SID24269910]
 HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]DRD2 gene product [Homo sapiens] [gi:4503385]
View
20
[SID14737103]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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21
[SID14737103]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
View
22
[SID14737103]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
23
[SID14737103]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
24
[SID14737103]
 Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
View
25
[SID14737103]
Potency 15.8489qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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26
[SID14737103]
Potency 15.8489qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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27
[SID14737103]
Concentration @ Maximum % Inhibition 50Screen for Chemicals that Inhibit the RAM Network - Dose Response with Drug Efflux Deficient Sensitized Control Strain [AID1305, Type: confirmatory]
View
28
[SID103904146]
CC50 50An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) using synethesized compounds (5) [AID493090, Type: confirmatory]
View
29
[SID14737103]
Potency 95.2834qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
View
30
[SID14737103]
Potency 95.2834qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
View
31
[SID24269910]
Potency qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
View
32
[SID24269910]
Potency qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]PIN1 gene product [Homo sapiens] [gi:5453898]
View
33
[SID14737103]
Potency qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase [AID1631, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
34
[SID14737103]
Potency qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase [AID1631, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
35
[SID14737103]
Potency qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase [AID1631, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
36
[SID14737103]
Potency qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
37
[SID14737103]
Potency qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
38
[SID14737103]
Potency qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]PKM gene product [Homo sapiens] [gi:33286418]
View
39
[SID14737103]
IC50 uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay. [AID1817, Type: confirmatory]plectin 1 [Homo sapiens] [gi:40849930]
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40
[SID14737103]
 Fluorescence polarization assay for PLK1 inhibitors [AID619, Type: screening]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
41
[SID14737103]
 Fluorescence polarization assay for PLK1 inhibitors [AID619, Type: screening]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
42
[SID14737103]
 High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1. [AID693, Type: screening]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
43
[SID14737103]
 High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1. [AID693, Type: screening]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
View
44
[SID14737103]
CC50 An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID2410, Type: confirmatory]
View
45
[SID14737103]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
46
[SID14737103]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
View
47
[SID14737103]
 Single Concentration Confirmation Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1894, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
48
[SID14737103]
 Single Concentration Confirmation Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1894, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
49
[SID14737103]
 Single Concentration Confirmation Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1894, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
View
50
[SID24269910]
Potency qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]
View