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BioActivity Data for Compound SMR000130516 (CID 9550413)

BioActivity Outcomes:
Active(4)
 
 
Inactive(810)
 
 
Inconclusive(21)
 
 
Unspecified(3)
 
 
Top Targets:
7tm 4(53)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(11)
 
 
G-alpha(8)
 
 
 
ANK(8)
 
 
 
BioAssay Types:
Screening(529)
 
 
 
 
 
Confirmatory(283)
 
 
 
 
 
Literature(12)
 
 
BioAssay Categories:
In vivo(1)
 
 
Biochemical(115)
 
 
Toxicity(13)
 
 
Cell-based(134)
 
 
 
Organism-base..(11)
 
 
BioActivity Types:
Potency(221)
 
 
 
 
 
IC50(44)
 
 
EC50(9)
 
 
AC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 691    Data Row: 838   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14733208]
Potency 16.3601qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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2
[SID14733208]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
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3
[SID14733208]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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4
[SID14733208]
CYP2C19 Assay [AID778, Type: screening]cytochrome P450 2C19 precursor [Homo sapiens] [gi:4503219]
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5
[SID14733208]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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6
[SID14733208]
Assay for HTS of Gi/Go-linked GPCRs using mGluR8: Primary Screening [AID488969, Type: screening]metabotropic glutamate receptor 8 [Rattus norvegicus] [gi:1575471]
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7
[SID24269525]
HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Primary Screen for Antagonists [AID485344, Type: screening]D(2) dopamine receptor isoform long [Homo sapiens] [gi:4503385]
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8
[SID24269525]
Potency 3.5481qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent) [AID485294, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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9
[SID14733208]
Potency 17.7828qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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10
[SID14733208]
Potency 35.4813qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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11
[SID24269525]
Potency 50.1187qHTS Assay to Find Inhibitors of Pin1 [AID504891, Type: confirmatory]peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Homo sapiens] [gi:5453898]
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12
[SID14733208]
Potency 56.2341qHTS Assay for Inhibitors of the HIV-1 protein Vpr [AID651644, Type: confirmatory]Vpr [Human immunodeficiency virus 1] [gi:28872817]
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13
[SID24269525]
Potency 89.1251qHTS of PTHR Inhibitors: Primary Screen [AID743266, Type: confirmatory]parathyroid hormone/parathyroid hormone-related peptide receptor precursor [Homo sapiens] [gi:296080761]
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14
[SID14733208]
Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of human platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (PAFAH1B2) [AID492953, Type: screening]platelet-activating factor acetylhydrolase IB subunit beta isoform b [Homo sapiens] [gi:296080766]
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15
[SID14733208]
IC50 Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents [AID1903, Type: confirmatory]large T antigen [Simian virus 40] [gi:297591903]
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16
[SID14733208]
LYP Inhibitors-an Autoimmunity Target - Primary screen [AID640, Type: screening]tyrosine-protein phosphatase non-receptor type 22 isoform 2 [Homo sapiens] [gi:301171662]
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17
[SID14733208]
LYP Activators-an Autoimmunity Target - Primary screen [AID697, Type: screening]tyrosine-protein phosphatase non-receptor type 22 isoform 2 [Homo sapiens] [gi:301171662]
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18
[SID14733208]
uHTS for Small Molecule Inhibitors of Eukaryotic Translation Initiation [AID782, Type: screening]eukaryotic translation initiation factor 4 gamma 1 isoform 4 [Homo sapiens] [gi:302699239]
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19
[SID14733208]
C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_SinglePoint_HTS_Activity [AID504423, Type: screening]LANA [Human herpesvirus 8] [gi:312275222]
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20
[SID14733208]
Potency qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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