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MLS000123156 (CID 9549435) - Compound BioActivity Data
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BioActivity Outcomes:
Active(28)
 
 
Inactive(700)
 
 
Inconclusive(20)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
7TM GPCR Srsx(21)
 
 
 
 
Bcl-2 like(12)
 
 
 
alkPPc(12)
 
 
G-alpha(10)
 
 
 
 
BioAssay Types:
Screening(510)
 
 
 
 
 
Confirmatory(217)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(154)
 
 
 
 
 
IC50(47)
 
 
 
EC50(10)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 687    Data Row: 750   Total Pages: 38   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID14722624]
Potency 0.0794qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS [AID588453, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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2
[SID14722624]
Potency 0.2512qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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3
[SID14722624]
Potency 0.317qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a: Hit Confirmation [AID588344, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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4
[SID14722624]
Potency 0.3359qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): Hit Validation in Primary Screen [AID652023, Type: confirmatory]thioredoxin reductase [Rattus norvegicus] [gi:8659577]
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5
[SID14722624]
Potency 3.5481qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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6
[SID14722624]
Potency 5.91Confirmation qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID2701, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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7
[SID14722624]
IC50 6.29946Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors [AID1417, Type: confirmatory]Mcl-1 [Homo sapiens] [gi:7582271]
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8
[SID14722624]
Potency 7.3078qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID14722624]
Potency 11.2202qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen [AID602199, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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10
[SID14722624]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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11
[SID14722624]
Potency 17.7828qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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12
[SID14722624]
Potency 17.7828HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails [AID540317, Type: confirmatory]chromobox protein homolog 1 [Homo sapiens] [gi:187960037]
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13
[SID14722624]
Potency 25.1189qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Texas Red Assay [AID602201, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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14
[SID14722624]
Potency 26.6795qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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15
[SID14722624]
Potency 28.1838qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Fluorescein Assay [AID602200, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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16
[SID14722624]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify nonselective agonists [AID651787, Type: screening]guanine nucleotide-binding protein subunit alpha-15 [Homo sapiens] [gi:156104883]
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17
[SID14722624]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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18
[SID14722624]
Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) [AID624467, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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19
[SID14722624]
Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput screening assay to identify hTAAR1 agonists that also desensitize TAAR1 receptor response. [AID651951, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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20
[SID14722624]
Fluorescence-based cell-based primary high throughput confirmation assay to identify agonists of the human trace amine associated receptor 1 (TAAR1) [AID651783, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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