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CHEBI:47379 (CID 9547919) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(1)
 
 
Top Targets:
PTPc(2)
 
 
 
BioAssay Types:
Literature(2)
 
 
Confirmatory(1)
 
 
BioActivity Types:
IC50(3)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103468152]
IC50 1.75Inhibitory concentration against protein-tyrosine phosphatase 1B by PNPP enzyme assay [AID254887, Type: Literature]Tyrosine-protein phosphatase non-receptor type 1 [gi:131467]
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2
[SID46394022]
IC50 1.75Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Structural Basis For Inhibition Of Protein Tyrosine Phosphatase 1b By Isothiazolidinone Heterocyclic Phosphonate Mimetics [gi:114793623]
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3
[SID103468152]
IC50 1749.85Inhibition of Homo sapiens (human) PTP1B expressed in Escherichia coli using PNPP as substrate [AID1115317, Type: confirmatory]Tyrosine-protein phosphatase non-receptor type 1 [gi:131467]
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