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ZINC00544706 (CID 946201) - Compound BioActivity Data
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BioActivity Outcomes:
Active(39)
 
 
Inactive(772)
 
 
Inconclusive(35)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(29)
 
 
 
7TM GPCR Srsx(24)
 
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
 
BioAssay Types:
Screening(590)
 
 
 
 
 
Confirmatory(224)
 
 
 
 
 
Literature(12)
 
 
 
BioActivity Types:
Potency(151)
 
 
 
 
 
IC50(48)
 
 
 
EC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 775    Data Row: 848   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7971145]
Potency 2.5929A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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2
[SID7971145]
Potency 2.9093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID7971145]
Potency 10.3225A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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4
[SID7971145]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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5
[SID7971145]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
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6
[SID7971145]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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7
[SID7971145]
Cell Proliferation & Viability (Cytotoxicity) Dose Response Assay 60K MLSMR [AID464, Type: confirmatory]
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8
[SID7971145]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) [AID430, Type: confirmatory]
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9
[SID7971145]
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen [AID626, Type: screening]
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10
[SID7971145]
Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
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11
[SID7971145]
Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
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12
[SID7971145]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
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13
[SID7971145]
Allosteric Modulators of D1 Receptors: Secondary Assay 2 [AID647, Type: other]
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14
[SID7971145]
Human Endothelial Cell Proliferation Assay in 384-well format [AID648, Type: screening]
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15
[SID7971145]
Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm [AID709, Type: screening]
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16
[SID7971145]
High Throughput Screen to Identify Compounds that Suppress the Growth of Human Colon Tumor Cells Lacking Oncogenic Beta Catenin Expression - Pilot Screen [AID823, Type: screening]
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17
[SID7971145]
High Throughput Screen to Identify Compounds that Suppress the Growth of Cells with a Deletion of the PTEN Tumor Suppressor - Pilot Screen [AID824, Type: screening]
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18
[SID7971145]
Human Lung Fibroblast Proliferation Assay [AID719, Type: screening]
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19
[SID7971145]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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20
[SID7971145]
Luminescence-based counterscreen assay for KLF5 inhibitors: cell-based high throughput screening assay to identify cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1825, Type: screening]
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