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BioActivity Data for Compound ZINC00544706 (CID 946201)

BioActivity Outcomes:
Active(39)
 
 
Inactive(776)
 
 
Inconclusive(35)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(54)
 
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
 
PTPc(9)
 
 
BioAssay Types:
Screening(590)
 
 
 
 
 
Confirmatory(227)
 
 
 
 
 
Literature(12)
 
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(1)
 
 
Biochemical(125)
 
 
Toxicity(12)
 
 
 
Cell-based(155)
 
 
 
 
Organism-base..(13)
 
 
BioActivity Types:
Potency(152)
 
 
 
 
 
IC50(50)
 
 
 
EC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 778    Data Row: 852   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7971145]
Potency 2.5929A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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2
[SID7971145]
Potency 2.9093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID7971145]
Potency 10.3225A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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4
[SID7971145]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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5
[SID7971145]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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6
[SID7971145]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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7
[SID7971145]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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8
[SID7971145]
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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9
[SID7971145]
HCS assay for microtubule stabilizers [AID2205, Type: screening]tubulin beta chain isoform b [Homo sapiens] [gi:29788785]
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10
[SID7971145]
HTS for Estrogen Receptor-beta Coactivator Binding inhibitors [AID633, Type: screening]estrogen receptor beta isoform 1 [Homo sapiens] [gi:10835013]
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11
[SID7971145]
High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1. [AID693, Type: screening]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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12
[SID7971145]
EC50 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) [AID430, Type: confirmatory]
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13
[SID7971145]
Cell Proliferation & Viability (Cytotoxicity) Dose Response Assay 60K MLSMR [AID464, Type: confirmatory]
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14
[SID7971145]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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15
[SID7971145]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
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16
[SID7971145]
Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen [AID626, Type: screening]
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17
[SID7971145]
Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
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18
[SID7971145]
Allosteric Modulators of D1 Receptors: Secondary Assay 2 [AID647, Type: other]
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19
[SID7971145]
Human Endothelial Cell Proliferation Assay in 384-well format [AID648, Type: screening]
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20
[SID7971145]
Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm [AID709, Type: screening]
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