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ZINC08329726 (CID 9454704) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(460)
 
 
Inconclusive(16)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(19)
 
 
7TM GPCR Srsx(15)
 
 
Firefly Luc l..(10)
 
 
 
Peptidase C48(8)
 
 
 
HSF(5)
 
 
 
 
BioAssay Types:
Screening(360)
 
 
 
 
Confirmatory(132)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(112)
 
 
 
 
 
IC50(11)
 
 
EC50(4)
 
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 463    Data Row: 507   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID56322134]
Potency 0.0023FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate and 500microM CoASH [AID602358, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID56322134]
Potency 0.0046FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM ATP [AID602364, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID56322134]
Potency 0.0058FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate [AID602357, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID56322134]
Potency 0.0179FLuc inhibitory activity for the follow-up compounds in a biochemical assay with a commercial detection reagent - BriteliteTM Plus (PerkinElmer) [AID602474, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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5
[SID56322134]
Potency 0.019qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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6
[SID56322134]
Potency 0.0461FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM D-luciferin [AID602365, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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7
[SID56322134]
Potency 0.0619FLuc inhibitory activity for the follow-up compounds in a biochemical assay with an in-house formulation of detection reagent [AID602475, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID56322134]
Potency 0.3162qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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9
[SID56322134]
Potency 0.3162qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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10
[SID56322134]
Potency 5.0354FLuc inhibitory activity for the follow-up compounds in a cell-based assay to assess the activity of miR-21 [AID602477, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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11
[SID56322134]
Potency 9.1905qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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12
[SID56322134]
EC50 35.962Luminescence Cell-Based Dose Response HTS to Identify Activators of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4 Neuroglioblastoma Cells [AID1999, Type: confirmatory]
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13
[SID56322134]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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14
[SID56322134]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
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15
[SID56322134]
7011-01_Antagonist_SinglePoint_HTS_Activity [AID720647, Type: screening]
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16
[SID56322134]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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17
[SID56322134]
Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488915, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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18
[SID56322134]
Single concentration confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488918, Type: screening]caspase-3 preproprotein [Homo sapiens] [gi:14790119]
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19
[SID56322134]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). [AID2098, Type: screening]Hsf1 protein [Mus musculus] [gi:62740231]
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20
[SID56322134]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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