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Azacitidine (CID 9444) - Compound BioActivity Data
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BioActivity Outcomes:
Active(270)
 
 
Inactive(927)
 
 
Inconclusive(254)
 
 
Unspecified(178)
 
 
Top Targets:
7TM GPCR Srx(43)
 
 
 
 
7TM GPCR Srsx(33)
 
 
 
NR LBD PPAR(26)
 
 
 
NR LBD ER(21)
 
 
 
 
NR LBD AR(19)
 
 
 
 
 
BioAssay Types:
Confirmatory(802)
 
 
 
 
 
Screening(397)
 
 
 
 
Literature(116)
 
 
 
 
Summary(49)
 
 
 
 
BioActivity Types:
Potency(642)
 
 
 
 
 
IC50(157)
 
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1083    Data Row: 1629   Total Pages: 82   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144213302]
Potency-Replicate_1 0.3857qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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2
[SID103555920]
IC50 0.409Compound was tested for its inhibitory activity against L1210 lymphoid leukemia [AID98149, Type: Literature]
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3
[SID56323580]
IC50_1_GAPDH 24hr 0.557Dose Response confirmation of uHTS small molecule Peg3 Promoter Inhibitor hits in screening - selectivity counter screen assays - Set 2 [AID651549_2, Type: confirmatory]Glyceraldehyde-3-phosphate dehydrogenase [gi:120649]
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4
[SID103555920]
IC50 0.63Antiproliferative activity against human A427 cells after 96 hrs by crystal violet assay [AID408558, Type: Literature]
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5
[SID144204583]
Potency-Replicate_1 0.6682qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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6
[SID144204583]
Potency-Replicate_1 0.7498qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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7
[SID144204583]
Potency-Replicate_1 0.8413qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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8
[SID144213302]
Potency-Replicate_1 1.0964qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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9
[SID144213302]
Potency-Replicate_1 1.2197qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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10
[SID56320704]
Potency 1.2538qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation using MMS Stimulated ELG1 [AID624249, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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11
[SID17390033]
Potency 1.2589Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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12
[SID144204583]
Potency 1.3685qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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13
[SID144213302]
Potency-Replicate_1 1.3685qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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14
[SID144213302]
Potency-Replicate_1 1.5355qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID743202, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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15
[SID144213302]
Potency-Replicate_1 1.5355qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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16
[SID103555920]
IC50 1.59Antiproliferative activity against human KYSE70 cells after 96 hrs by crystal violet assay [AID408559, Type: Literature]
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17
[SID56323580]
Potency 1.636qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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18
[SID103555920]
IC50 1.73Antiproliferative activity against human 5637 cells after 96 hrs by crystal violet assay [AID408557, Type: Literature]
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19
[SID144213302]
Potency-Replicate_1 1.7376qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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20
[SID144213302]
Ratio Potency (uM) 1.7903qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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