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BioActivity Data for Compound perfluorodecalin (CID 9386)

BioActivity Outcomes:
Active(3)
 
 
Inactive(200)
 
 
Inconclusive(13)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD VDR(5)
 
 
 
NR LBD TR(5)
 
 
BioAssay Types:
Confirmatory(113)
 
 
 
 
 
Literature(62)
 
 
 
 
Summary(27)
 
 
 
Screening(10)
 
 
BioAssay Categories:
Biochemical(1)
 
 
Toxicity(6)
 
 
 
 
Cell-based(8)
 
 
BioActivity Types:
Potency(127)
 
 
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 155    Data Row: 218   Total Pages: 11   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205827]
Potency 16.7889qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID144205827]
Potency-Replicate_1 21.1317qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID29217729]
Potency 79.4328Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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4
[SID170466377]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 blue channel [AID1117304, Type: confirmatory]
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5
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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6
[SID29217729]
Potency 5.6234qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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7
[SID144205827]
Potency-Replicate_1 7.4978qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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8
[SID170466377]
Ac50 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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9
[SID170466377]
AC50 (uM) 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel [AID1117305, Type: confirmatory]
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10
[SID170466377]
Ac50 22.3872qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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11
[SID170466377]
AC50 (uM) 22.3872qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
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12
[SID144205827]
AhR Potency (uM) qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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13
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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14
[SID29217729]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]menin isoform 1 [Homo sapiens] [gi:18860839]
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15
[SID170466377]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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16
[SID29217729]
Potency qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide [AID1768, Type: confirmatory]histone-lysine N-methyltransferase 2A isoform 2 precursor [Homo sapiens] [gi:56550039]
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17
[SID29217729]
Potency qHTS of Trypanosoma Brucei Inhibitors [AID624173, Type: confirmatory]hypothetical protein, conserved [Trypanosoma brucei] [gi:62359610]
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18
[SID29217729]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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19
[SID29217729]
Potency qHTS for Inhibitors of Glutaminase (GLS) [AID624170, Type: confirmatory]GLS protein [Homo sapiens] [gi:71051501]
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20
[SID29217729]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation [AID492961, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:72386991]
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