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BioActivity Data for Compound perfluorodecalin (CID 9386)

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BioActivity Outcomes:
Active(3)
 
 
Inactive(179)
 
 
Inconclusive(13)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Confirmatory(102)
 
 
 
 
Literature(62)
 
 
 
 
Summary(24)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(116)
 
 
 
 
AC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 133    Data Row: 196   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205827]
Potency 16.7889qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID144205827]
Potency-Replicate_1 21.1317qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID29217729]
Potency 79.4328Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein, partial [Homo sapiens] [gi:118600387]
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4
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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5
[SID29217729]
Potency 5.6234qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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6
[SID144205827]
Potency-Replicate_1 7.4978qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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7
[SID170466377]
Ac50 17.7828qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel [AID1117312, Type: confirmatory]
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8
[SID170466377]
Ac50 22.3872qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel [AID1117310, Type: confirmatory]
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9
[SID170466377]
Ratio Potency (uM) qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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10
[SID170466377]
Ac50 qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, blue channel [AID1117314, Type: confirmatory]
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11
[SID144205827]
Ratio Potency (uM) qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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12
[SID144205827]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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13
[SID144205827]
ATAD5 Potency (uM) qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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14
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the glucocorticoid receptor (GR) signaling pathway [AID720691, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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15
[SID170466377]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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16
[SID170466377]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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17
[SID170466377]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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18
[SID170466377]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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19
[SID170466377]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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20
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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