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perfluorodecalin (CID 9386) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(170)
 
 
Inconclusive(18)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(8)
 
 
 
NR LBD ER(7)
 
 
NR LBD AR(7)
 
 
NR LBD TR(5)
 
 
NR LBD VDR(5)
 
 
 
BioAssay Types:
Confirmatory(98)
 
 
 
 
Literature(62)
 
 
 
 
Summary(24)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(115)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 129    Data Row: 192   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144205827]
Potency 16.7889qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID144205827]
Potency-Replicate_1 21.1317qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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3
[SID29217729]
Potency 79.4328Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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4
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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5
[SID29217729]
Potency 5.6234qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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6
[SID144205827]
Potency-Replicate_1 7.4978qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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7
[SID144205827]
Potency-Replicate_1 qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
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8
[SID144205827]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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9
[SID144205827]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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10
[SID144205827]
Ratio Potency (uM) qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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11
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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12
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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13
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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14
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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15
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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16
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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17
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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18
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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19
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cell free culture [AID720684, Type: confirmatory]
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20
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cell free culture [AID720685, Type: confirmatory]
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21
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cell free culture [AID720686, Type: confirmatory]
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22
[SID144205827]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HepG2 cells [AID720687, Type: confirmatory]
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23
[SID144205827]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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24
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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25
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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26
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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27
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
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28
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
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29
[SID144205827]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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30
[SID144205827]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
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31
[SID170466377]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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32
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_59, Type: Literature]
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33
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_60, Type: Literature]
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34
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_61, Type: Literature]
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35
[SID29217729]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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36
[SID29217729]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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37
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the rad50 strain [AID155, Type: other]
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38
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the mec2-1 strain [AID157, Type: other]
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39
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the sgs1 mgt1 strain [AID161, Type: other]
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40
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the cln2 rad14 strain [AID165, Type: other]
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41
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the bub3 strain [AID167, Type: other]
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42
[SID401356]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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43
[SID29217729]
Potency S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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44
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_1, Type: Literature]
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45
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_2, Type: Literature]
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46
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_3, Type: Literature]
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47
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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48
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_5, Type: Literature]
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49
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_6, Type: Literature]
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50
[SID29217729]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_7, Type: Literature]
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