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BioActivity Data for Compound Ribonuclease, Pancreatic (CID 9369)

BioActivity Outcomes:
Active(8)
 
 
Inactive(64)
 
 
Inconclusive(1)
 
 
Unspecified(8)
 
 
Top Targets:
MFS(7)
 
 
BioAssay Types:
Confirmatory(55)
 
 
Literature(18)
 
 
 
 
 
BioAssay Categories:
In vitro(13)
 
 
 
In vivo(2)
 
 
Biochemical(6)
 
 
ADME(1)
 
 
Cell-based(8)
 
 
 
BioActivity Types:
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 81    Data Row: 81   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103182320]
In vitro carbonic anhydrase activation in human cloned Carbonic anhydrase I (hCA I) [AID50348, Type: Literature]
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2
[SID103182320]
Tested in vitro for activation of Human cloned isozyme carbonic anhydrase I (hCA I) [AID50347, Type: Literature]
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3
[SID103182320]
In vitro carbonic anhydrase IV activation in bovine lung microsomes. [AID48117, Type: Literature]
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4
[SID103182320]
Tested in vitro for activation of carbonic anhydrase IV (bCA IV), purified from bovine lung microsomes [AID48116, Type: Literature]
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5
[SID103182320]
In vitro carbonic anhydrase activation in human cloned Carbonic anhydrase II (hCA II) [AID47897, Type: Literature]
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6
[SID103182320]
Tested in vitro for activation of Human cloned isozyme carbonic anhydrase II (hCA II) [AID47753, Type: Literature]
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7
[SID103182320]
Antioxidant activity in Wistar rat erythrocytes assessed as prolongation of initial inhibition period-lag phase of t-BuOOH-induced hemolysis at 10 mM preincubated for 30 mins before induction measured up to 5 hrs by spectrophotometry [AID633135, Type: Literature]
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8
[SID103182320]
Protection against hypoxia-induced brain damage in Wistar rat ischemia-reperfusion injury model assessed as reduction of cerebral infarct volume at 1 g/kg, iv administered at beginning of reperfusion and again after 6 hrs measured 24 hrs after reperfusion [AID671304, Type: Literature]
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9
[SID103182320]
Half life in human serum at 0.5 mM by RP-HPLC analysis [AID671295, Type: Literature]
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10
[SID103182320]
TP_TRANSPORTER: inhibition of fMLP uptake (fMLP: 0.1 uM, Carnosine: 10000 uM) in Caco-2 cells [AID680670, Type: Literature]Solute carrier family 15 member 1 [gi:1172435]
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11
[SID103182320]
TP_TRANSPORTER: inhibition of VACV uptake (VACV: 0.2 uM, Carnosine: 10000 uM) in Xenopus laevis oocytes [AID680832, Type: Literature]Solute carrier family 15 member 1 [gi:1172435]
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12
[SID103182320]
TP_TRANSPORTER: uptake in Xenopus laevis oocytes [AID681152, Type: Literature]Solute carrier family 15 member 1 [gi:1172435]
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13
[SID103182320]
TP_TRANSPORTER: inhibition of Cephradine uptake (Cephradine: 3000 uM, Carnosine: 10000 uM) in Xenopus laevis oocytes [AID679867, Type: Literature]Solute carrier family 15 member 1 [gi:1730492]
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14
[SID103182320]
TP_TRANSPORTER: inhibition of Ceftibuten uptake (Ceftibuten: 1000 uM, Carnosine: 10000 uM) in Xenopus laevis oocytes [AID679880, Type: Literature]Solute carrier family 15 member 1 [gi:1730492]
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15
[SID103182320]
TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.010? uM, Carnosine: 500 uM) in OCTN2-expressing HEK293 cells [AID681683, Type: Literature]Solute carrier family 22 member 5 [gi:8928257]
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16
[SID103182320]
TP_TRANSPORTER: uptake (electrogenesis) in Xenopus laevis oocytes [AID678975, Type: Literature]Solute carrier family 15 member 2 [gi:62901106]
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17
[SID103182320]
Reduction of ischemia-reperfusion-induced TNFalpha level increase in Wistar rat serum at 1 g/kg, iv by ELISA [AID671306, Type: Literature]
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18
[SID481668]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice [AID330, Type: other]
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19
[SID481668]
NCI In Vivo Anticancer Drug Screen. Data for tumor model B16 Melanoma (intraperitoneal) in B6C3F1 mice [AID200, Type: other]
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20
[SID481668]
NCI Yeast Anticancer Drug Screen. Data for the mlh1 rad18 strain [AID175, Type: other]
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