naphthalene (CID 931) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(61)
 
 
Inactive(623)
 
 
Inconclusive(9)
 
 
Unspecified(29)
 
 
Top Targets:
7TM GPCR Srx(14)
 
 
NR LBD PPAR(10)
 
 
NR LBD TR(8)
 
 
p450(6)
 
 
 
 
7TM GPCR Srsx(6)
 
 
BioAssay Types:
Confirmatory(285)
 
 
 
 
Screening(247)
 
 
Literature(159)
 
 
 
 
 
BioActivity Types:
Potency(238)
 
 
 
 
IC50(13)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 597    Data Row: 722   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179262]
IC50 25Inhibitory concentration against human cytochrome P450 2A6 [AID241172, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
View
2
[SID103179262]
IC50 25.0034Inhibition of human CYP2A6 [AID420671, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
View
3
[SID48414084]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
4
[SID48414084]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
5
[SID48414084]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
6
[SID48414989]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
7
[SID85209850]
 Ligands of bioamine (Class A) GPCRs [AID2062, Type: other]
View
8
[SID85209850]
 Ligands of peptide (Class A) GPCRs [AID2063, Type: other]
View
9
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at comma stage of embryo at 200 uM dissolved in soybean oil [AID513049, Type: Literature]
View
10
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 1.5 fold stage of embryo at 200 uM dissolved in soybean oil [AID513050, Type: Literature]
View
11
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 2-fold stage of embryo at 200 uM dissolved in soybean oil [AID513051, Type: Literature]
View
12
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 4-fold stage of embryo at 200 uM dissolved in soybean oil [AID513052, Type: Literature]
View
13
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at comma stage of embryo at 250 uM dissolved in soybean oil [AID513053, Type: Literature]
View
14
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 1.5 fold stage of embryo at 250 uM dissolved in soybean oil [AID513054, Type: Literature]
View
15
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 2-fold stage of embryo at 250 uM dissolved in soybean oil [AID513055, Type: Literature]
View
16
[SID103179262]
 Antiapoptotic activity against wild-type Caenorhabditis elegans assessed as reduction in number of cell cropses at 4-fold stage of embryo at 250 uM dissolved in soybean oil [AID513056, Type: Literature]
View
17
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at comma stage of embryo at 200 uM dissolved in soybean oil [AID513057, Type: Literature]
View
18
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at 1.5-fold stage of embryo at 200 uM dissolved in soybean oil [AID513058, Type: Literature]
View
19
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at 2-fold stage of embryo at 200 uM dissolved in soybean oil [AID513059, Type: Literature]
View
20
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at comma 4-fold of embryo at 200 uM dissolved in soybean oil [AID513060, Type: Literature]
View
21
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at comma stage of embryo at 250 uM dissolved in soybean oil [AID513061, Type: Literature]
View
22
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at 1.5-fold stage of embryo at 250 uM dissolved in soybean oil [AID513062, Type: Literature]
View
23
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at 2-fold stage of embryo at 250 uM dissolved in soybean oil [AID513063, Type: Literature]
View
24
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans engulfment-defective ced-1(e1735) mutant assessed as reduction in number of cell cropses at comma 4-fold of embryo at 250 uM dissolved in soybean oil [AID513064, Type: Literature]
View
25
[SID103179262]
 Antiapoptotic activity against hermaphroditic wild type Caenorhabditis elegans carrying smls26 transgene assessed as inhibition of male-specific CEM neurons death at 200 mM after 2 hrs [AID513065, Type: Literature]
View
26
[SID103179262]
 Antiapoptotic activity against hermaphroditic Caenorhabditis elegans ced-3(n2438) mutant carrying smls26 transgene assessed as inhibition of male-specific CEM neurons death at 200 mM after 2 hrs [AID513066, Type: Literature]
View
27
[SID103179262]
 Antiapoptotic activity against hermaphroditic Caenorhabditis elegans ced-3(n2433) mutant carrying smls26 transgene assessed as inhibition of male-specific CEM neurons death at 200 mM after 2 hrs [AID513067, Type: Literature]
View
28
[SID103179262]
 Antiapoptotic activity against hermaphroditic wild type Caenorhabditis elegans carrying smls26 transgene assessed as inhibition of male-specific CEM neurons death at 250 mM after 2 hrs [AID513068, Type: Literature]
View
29
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant carrying smls26 transgene assessed as survival of CEM neurons at 250 mM after 2 hrs [AID513069, Type: Literature]
View
30
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells kept in anterior pharynx in gaseous compound exposed air tight plastic storage box at 4 uM [AID512734, Type: Literature]
View
31
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx kept in drug exposed air tight plastic storage box at 0.6 g/L in air [AID512733, Type: Literature]
View
32
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx kept in drug exposed air tight plastic storage box at 0.06 g/L in air [AID512732, Type: Literature]
View
33
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2433) mutant carrying smls26 transgene assessed as survival of CEM neurons at 250 mM after 2 hrs [AID513070, Type: Literature]
View
34
[SID103179262]
 Antiapoptotic activity against wild type Caenorhabditis elegans carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 200 mM after 2 hrs [AID513071, Type: Literature]
View
35
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 200 mM after 2 hrs [AID513072, Type: Literature]
View
36
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2433) mutant carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 200 mM after 2 hrs [AID513073, Type: Literature]
View
37
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 250 mM after 2 hrs [AID513074, Type: Literature]
View
38
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 250 mM after 2 hrs [AID513075, Type: Literature]
View
39
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2433) mutant carrying nis96 transgene assessed as number of extra VC- cells in postembryonic stage at 250 mM after 2 hrs [AID513076, Type: Literature]
View
40
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-1 embryo in absence of CED-4 [AID513077, Type: Literature]
View
41
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-1 embryo in absence of CED-4 [AID513078, Type: Literature]
View
42
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-2 embryo in absence of CED-4 [AID513079, Type: Literature]
View
43
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-2 embryo in absence of CED-4 [AID513080, Type: Literature]
View
44
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-3 embryo in absence of CED-4 [AID513081, Type: Literature]
View
45
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-3 embryo in absence of CED-4 [AID513082, Type: Literature]
View
46
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of (smls111) transgenic embryo in absence of CED-4 [AID513083, Type: Literature]
View
47
[SID103179262]
 Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of (smls111) transgenic transgenic embryo in absence of CED-4 [AID513084, Type: Literature]
View
48
[SID48414084]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
49
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 50 uM dissolved in water [AID512727, Type: Literature]
View
50
[SID103179262]
 Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 75 uM dissolved in water [AID512728, Type: Literature]
View