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BioActivity Data for Compound naphthalene (CID 931)

BioActivity Outcomes:
Active(61)
 
 
Inactive(949)
 
 
Inconclusive(15)
 
 
Unspecified(35)
 
 
Top Targets:
7tm 4(36)
 
 
NR LBD PPAR(28)
 
 
NR LBD ER(25)
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(17)
 
 
BioAssay Types:
Confirmatory(493)
 
 
 
 
Screening(300)
 
 
Literature(172)
 
 
 
 
 
Summary(63)
 
 
BioAssay Categories:
In vivo(2)
 
 
Biochemical(101)
 
 
 
Toxicity(64)
 
 
 
 
ADME(15)
 
 
 
Cell-based(92)
 
 
Organism-base..(9)
 
 
BioActivity Types:
Potency(493)
 
 
 
 
IC50(15)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 739    Data Row: 1060   Total Pages: 53   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179262]
IC50 25Inhibitory concentration against human cytochrome P450 2A6 [AID241172, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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2
[SID103179262]
IC50 25.0035Inhibition of human CYP2A6 [AID420671, Type: Literature]Cytochrome P450 2A6 [gi:308153612]
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3
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512737, Type: Literature]
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4
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) G474R mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512738, Type: Literature]
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5
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2447) S446L mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512739, Type: Literature]
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6
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2436) L269 mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512740, Type: Literature]
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7
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-4(n2273) mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512741, Type: Literature]
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8
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-8(n1891) mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512742, Type: Literature]
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9
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-9(n1950) mutant assessed as number of extra cells in anterior pharynx L3 and L4 larvae at 200 mM dissolved in soybean oil [AID512743, Type: Literature]
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10
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-1 embryo in absence of CED-4 [AID513078, Type: Literature]
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11
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-2 embryo in absence of CED-4 [AID513079, Type: Literature]
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12
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-2 embryo in absence of CED-4 [AID513080, Type: Literature]
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13
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-3 embryo in absence of CED-4 [AID513081, Type: Literature]
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14
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of transgenic line-3 embryo in absence of CED-4 [AID513082, Type: Literature]
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15
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-1(e1735) mutant assessed as number of cell corpses in 4-fold stage of (smls111) transgenic embryo in absence of CED-4 [AID513083, Type: Literature]
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16
[SID103179262]
Suppression of activated CED-3-induced apoptosis expressed in Caenorhabditis elegans ced-4(n1162) mutant assessed as number of cell corpses in 4-fold stage of (smls111) transgenic embryo in absence of CED-4 [AID513084, Type: Literature]
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17
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 75 uM dissolved in water [AID512728, Type: Literature]
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18
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 100 uM dissolved in water [AID512729, Type: Literature]
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19
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 125 uM dissolved in water [AID512730, Type: Literature]
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20
[SID103179262]
Antiapoptotic activity against Caenorhabditis elegans ced-3(n2438) mutant assessed as increase in number of extra cells in anterior pharynx at 150 uM dissolved in water [AID512731, Type: Literature]
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