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BioActivity Data for Compound gamma-Tocopherol (CID 92729)

BioActivity Outcomes:
Active(3)
 
 
Inactive(79)
 
 
Inconclusive(5)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(4)
 
 
NR LBD TR(3)
 
 
PAS(2)
 
 
BioAssay Types:
Confirmatory(64)
 
 
 
Summary(15)
 
 
 
Screening(5)
 
 
Literature(4)
 
 
 
BioActivity Types:
Potency(67)
 
 
 
IC50(10)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 88    Data Row: 88   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163337266]
Antioxidant activity assessed as DPPH free radical scavenging activity [AID690600, Type: Literature]
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2
[SID163337266]
Antioxidant activity assessed as ABTS+ free radical scavenging activity by TEAC assay [AID690612, Type: Literature]
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3
[SID163337266]
Antioxidant activity assessed as ferric ion reducing power by FRAP method [AID690597, Type: Literature]
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4
[SID163337266]
Antioxidant activity assessed as nitration product at 1:1 compound to phenol concentration [AID690599, Type: Literature]
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5
[SID144207108]
Potency 3.9811qHTS Assay for Identifying Gametocytocidal Compounds [AID743244, Type: confirmatory]
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6
[SID144207108]
Potency-Replicate_1 8.4852qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID225144337]
IC50 10VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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8
[SID225144337]
IC50 10VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (viability)-IC50 [AID1117324, Type: confirmatory]
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9
[SID144207108]
Potency-Replicate_1 13.3332qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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10
[SID225144337]
IC50 20HT-29 viability from Cell TiterGlo-IC50 [AID1117330, Type: confirmatory]
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11
[SID225144337]
IC50 20HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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12
[SID225144337]
IC50 20Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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13
[SID225144337]
IC50 20SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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14
[SID225144337]
IC50 20GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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15
[SID225144337]
IC50 20RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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16
[SID225144337]
IC50 20SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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17
[SID225144337]
IC50 20DLD-1 viability from Cell TiterGlo-IC50 [AID1117352, Type: confirmatory]
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18
[SID144207108]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
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19
[SID144207108]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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20
[SID144207108]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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