Cyclopentanes (CID 9253) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Inactive(148)
 
 
Inconclusive(2)
 
 
Unspecified(2)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
NR LBD ROR li..(3)
 
 
NR LBD VDR(2)
 
 
BioAssay Types:
Confirmatory(141)
 
 
 
Literature(2)
 
 
 
BioActivity Types:
Potency(105)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 144    Data Row: 152   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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2
[SID134460987]
 Octanol-water partition coefficient, log P of the compound [AID603957, Type: Literature]
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3
[SID17389080]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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4
[SID17389080]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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5
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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6
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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7
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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8
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
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9
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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10
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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11
[SID17389080]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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12
[SID17389080]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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13
[SID17389080]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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14
[SID17389080]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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15
[SID17389080]
Potency qHTS assay for small molecule agonists of farnesoid X receptor signaling [AID588527, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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16
[SID17389080]
Potency VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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17
[SID17389080]
Potency qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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18
[SID17389080]
 JNK3 AlphaScreen Assay [AID530, Type: confirmatory]Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase [gi:2499604]
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19
[SID17389080]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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20
[SID17389080]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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21
[SID17389080]
Potency qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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22
[SID17389080]
 Cell Viability - N2a [AID540, Type: confirmatory]
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23
[SID17389080]
 Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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24
[SID17389080]
 Cell Viability - HUV-EC-C [AID542, Type: confirmatory]
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25
[SID17389080]
 Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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26
[SID17389080]
 Cell Viability - SH-SY5Y [AID544, Type: confirmatory]
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27
[SID17389080]
 Cell Viability - Renal Proximal Tubule [AID545, Type: confirmatory]
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28
[SID17389080]
 Cell Viability - Mesenchymal [AID546, Type: confirmatory]
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29
[SID17389080]
 Cell Viability - HepG2 [AID433, Type: confirmatory]
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30
[SID17389080]
 Cell Viability - MRC5 [AID434, Type: confirmatory]
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31
[SID17389080]
 Cell Viability - SK-N-SH [AID435, Type: confirmatory]
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32
[SID17389080]
 qHTS Assay for Disrupters of an Hsp90 Co-Chaperone Interaction [AID595, Type: confirmatory]
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33
[SID17389080]
 qHTS Assay for Inhibitors of DNA Polymerase III Holoenzyme System [AID603, Type: confirmatory]
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34
[SID17389080]
 Cellular Toxicity (caspase-3) HepG2 [AID654, Type: confirmatory]
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35
[SID17389080]
 Cellular Toxicity (caspase-3) Jurkat [AID655, Type: confirmatory]
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36
[SID17389080]
 Cellular Toxicity (caspase-3) HUV-EC-C [AID656, Type: confirmatory]
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37
[SID17389080]
 Cellular Toxicity (caspase-3) SHSY5Y [AID657, Type: confirmatory]
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38
[SID17389080]
 Cellular Toxicity (caspase-3) BJ [AID658, Type: confirmatory]
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39
[SID17389080]
 Cellular Toxicity (caspase-3) MRC-5 [AID659, Type: confirmatory]
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40
[SID17389080]
 Cellular Toxicity (caspase-3) Mesangial [AID660, Type: confirmatory]
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41
[SID17389080]
 Cellular Toxicity (caspase-3) SK-N-SH [AID661, Type: confirmatory]
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42
[SID17389080]
 Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
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43
[SID17389080]
 Cellular Toxicity (caspase-3) H-4-II-E [AID663, Type: confirmatory]
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44
[SID17389080]
 Cellular Toxicity (caspase-3) Hek293 [AID664, Type: confirmatory]
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45
[SID17389080]
 Cellular Toxicity (caspase-3) N2a [AID665, Type: confirmatory]
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46
[SID17389080]
 Cell Viability - Hek293 [AID427, Type: confirmatory]
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47
[SID17389080]
 Cell Viability - Jurkat [AID426, Type: confirmatory]
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48
[SID17389080]
 Cell Viability - BJ [AID421, Type: confirmatory]
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49
[SID17389080]
 Cellular Toxicity (caspase-3) NIH 3T3 [AID666, Type: confirmatory]
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50
[SID17389080]
Potency MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells [AID946, Type: confirmatory]
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