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monocerin (CID 92267) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(2)
 
 
Inactive(15)
 
 
Unspecified(18)
 
 
Top Targets:
Myc N(1)
 
 
Bcl-2 like(1)
 
 
STAT bind(1)
 
 
P53(1)
 
 
PTZ00435(1)
 
 
BioAssay Types:
Literature(20)
 
 
 
Screening(15)
 
 
BioActivity Types:
IC50(11)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 35    Data Row: 35   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103586272]
IC50 0.68Antimalarial activity against multidrug-resistant Plasmodium falciparum K1 [AID362771, Type: Literature]
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2
[SID103586272]
IC50 10.8Antioxidant activity assessed as trolox equivalent of peroxy radical scavenging activity at 1 uM by ORAC assay [AID568571, Type: Literature]
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3
[SID103586272]
IC50 16.2Inhibition of CYP19 [AID568566, Type: Literature]
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4
[SID103586272]
IC50 130Antioxidant activity in human HL60 cells assessed as inhibition of TPA-induced superoxide anion radical production [AID568569, Type: Literature]
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5
[SID103586272]
IC50 153Cytotoxicity against human MOLT3 cells by XTT assay [AID568565, Type: Literature]
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6
[SID103586272]
IC50 162.1Cytotoxicity against human HepG2 cells by MTT assay [AID568563, Type: Literature]
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7
[SID103586272]
IC50 162.1Cytotoxicity against human A549 cells by MTT assay [AID568564, Type: Literature]
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8
[SID103586272]
IC50 162.1Cytotoxicity against human HuCCA1 cells by MTT assay [AID568562, Type: Literature]
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9
[SID103586272]
IC50 324Antioxidant activity assessed as DPPH radical scavenging activity [AID568567, Type: Literature]
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10
[SID103586272]
IC50 648Antioxidant activity assessed as inhibition of xanthine-xanthine oxidase generated superoxide anion radical production [AID568568, Type: Literature]
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11
[SID103586272]
IC50 648Inhibition of Xanthine oxidase [AID568570, Type: Literature]
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12
[SID103586272]
Cytotoxicity against human BT474 cells at 20 ug/mL by MTT assay [AID362772, Type: Literature]
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13
[SID103586272]
Cytotoxicity against human CHAGO cells at 20 ug/mL by MTT assay [AID362773, Type: Literature]
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14
[SID103586272]
Cytotoxicity against human HepG2 cells at 20 ug/mL by MTT assay [AID362774, Type: Literature]
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15
[SID103586272]
Cytotoxicity against human KATO3 cells at 20 ug/mL by MTT assay [AID362775, Type: Literature]
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16
[SID103586272]
Cytotoxicity against human SW620 cells at 20 ug/mL by MTT assay [AID362776, Type: Literature]
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17
[SID103586272]
Antimicrobial activity against Escherichia coli by agar diffusion method [AID406146, Type: Literature]
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18
[SID103586272]
Antimicrobial activity against Bacillus megaterium by agar diffusion method [AID406147, Type: Literature]
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19
[SID103586272]
Antimicrobial activity against Microbotryum violaceum by agar diffusion method [AID406148, Type: Literature]
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20
[SID103586272]
Antimicrobial activity against Chlorella fusca by agar diffusion method [AID406149, Type: Literature]
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21
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Re-Activators of the P53 Mutant Pathway Measured in Cell-Based System Using Plate Reader - 2071-01_Activator_SinglePoint_HTS_Activity [AID624151, Type: screening]
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22
[SID85843377]
Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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23
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of STK33 [AID2330, Type: screening]serine/threonine kinase 33 [Homo sapiens] [gi:12830367]
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24
[SID85843377]
SMM STAT-3 Measured in Biochemical System Using Small Molecule MicroArray - 2076-01_Other_SinglePoint_HTS_Activity_Set2 [AID624138, Type: screening]signal transducer and activator of transcription 3 isoform 1 [Homo sapiens] [gi:21618340]
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25
[SID85843377]
NF-KappaB Measured in Biochemical System Using Small Molecule MicroArray - 2080-01_Other_SinglePoint_HTS_Activity [AID624139, Type: screening]nuclear factor NF-kappa-B p105 subunit isoform 1 [Homo sapiens] [gi:34577122]
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26
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of MITF [AID2240, Type: screening]microphthalmia-associated transcription factor isoform 1 [Homo sapiens] [gi:38156699]
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27
[SID85843377]
Development of IDH1/2 inhibitors (CTD2project) Measured in Biochemical System Using Plate Reader - 2107-01_Inhibitor_SinglePoint_HTS_Activity [AID624101, Type: screening]Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens] [gi:62203298]
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28
[SID85843377]
SMM c-myc Measured in Biochemical System Using Small Molecule MicroArray - 2081-01_Other_SinglePoint_HTS_Activity [AID624141, Type: screening]myc proto-oncogene protein [Homo sapiens] [gi:71774083]
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29
[SID85843377]
mutant P53 Measured in Biochemical System Using Small Molecule MicroArray - 2077-01_Other_SinglePoint_HTS_Activity [AID624136, Type: screening]mutant p53 [Homo sapiens] [gi:208342286]
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30
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of A1 [AID2241, Type: screening]Chain A, Human Bcl2-A1 In Complex With Bim-Bh3 Peptide [gi:167013344]
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31
[SID85843377]
Luminescence Cell-Based Primary HTS to Measure Viability of BJeLR cells [AID2275, Type: screening]
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32
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Inhibitors of the Sonic Hedgehog Signaling Pathway [AID2313, Type: screening]
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33
[SID85843377]
Luminescence Cell-Based Primary HTS to Identify Activators of the Reversal of PD-1 Mediated Inhibitors of T-Cell Inhibition [AID2316, Type: screening]
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34
[SID85843377]
Luminescence Homogenous Primary HTS to Identify Inhibitors of STK33 Activity [AID2322, Type: screening]
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35
[SID85843377]
Fluorescence Cell-Based Primary HTS to Measure Inhibition of Y box Binding Protein 1 Expression [AID434959, Type: screening]
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