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dibenz(b,f)(1,4)oxazepine (CID 9213) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(11)
 
 
Unspecified(2)
 
 
Top Targets:
ANK(5)
 
 
 
 
crotonase-lik..(1)
 
 
Autoind synth(1)
 
 
Chorismate bi..(1)
 
 
23DHB-AMP lg(1)
 
 
BioAssay Types:
Literature(8)
 
 
 
 
Screening(1)
 
 
BioActivity Types:
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 15   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103757004]
EC50 0.0003Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay [AID516893, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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2
[SID103757004]
EC50 0.000302Activation of human TRPA1 channel [AID482136, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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3
[SID103757004]
Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as threshold concentration after 1 min [AID516894, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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4
[SID103757004]
Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as concentration required to incapacitate 50% of the population exposed to tear gas [AID516895, Type: Literature]Transient receptor potential cation channel subfamily A member 1 [gi:313104269]
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5
[SID146008]
NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice [AID328, Type: other]
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6
[SID103757004]
Agonist activity at TRPM8 [AID516901, Type: Literature]
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7
[SID92130071]
A screen for compounds that inhibit replication of Vibrio cholerae chromosome II [AID504770, Type: other]hypothetical protein VC_A0002 [Vibrio cholerae O1 biovar El Tor str. N16961] [gi:9657380]
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8
[SID92130071]
A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]1,4-dihydroxy-2-naphthoyl-CoA synthase [Mycobacterium tuberculosis H37Rv] [gi:15607688]
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9
[SID92130071]
A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus [AID720641, Type: other]anion-binding protein [Staphylococcus aureus subsp. aureus Mu50] [gi:15923709]
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10
[SID92130071]
Inhibition of the Burkholderia mallei acyl-homoserine lactone synthase BmaI1 [AID720554, Type: other]autoinducer synthetase family protein [Burkholderia mallei ATCC 23344] [gi:52423132]
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11
[SID92130071]
A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities [AID588519, Type: Literature]Chain A, Poliovirus Polymerase With Gtp [gi:52695378]
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12
[SID92130071]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme MbtI [AID493033, Type: other]Isochorismate synthase/isochorismate-pyruvate lyase mbtI [gi:81706979]
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13
[SID92130071]
A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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14
[SID92130071]
A screen for compounds that inhibit the activity of Staphylococcus aureus DNA helicase [AID485395, Type: other]replicative DNA helicase [Staphylococcus aureus subsp. aureus JH1] [gi:150392496]
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15
[SID103757004]
Agonist activity at human TRPV1 [AID516900, Type: Literature]Transient receptor potential cation channel subfamily V member 1 [gi:296452849]
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