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BioActivity Data for Compound QUINAZOLINE (CID 9210)

BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
DHFR(1)
 
 
BioAssay Types:
Literature(4)
 
 
 
BioAssay Categories:
Biochemical(4)
 
 
 
Cell-based(1)
 
 
BioActivity Types:
IC50(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103238931]
IC50 0.0023Inhibition of NADH fumarate reductase in Echinococcus multilocularis protoscolece [AID422946, Type: Literature]
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2
[SID103238931]
IC50 0.027Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells [AID69425, Type: Literature]
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3
[SID103238931]
The concentration required to inhibit dihydrofolate reductase in rat liver [AID58159, Type: Literature]
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4
[SID103238931]
Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 [AID1159387, Type: other]
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5
[SID103238931]
Inhibition of liver dihydrofolate reductase (unknown origin) [AID1145385, Type: Literature]Dihydrofolate reductase [gi:118992]
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