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3,7-dichloro-8-quinolinecarboxylic acid (CID 91739) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(115)
 
 
Inconclusive(10)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
NR LBD Fxr(6)
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
Summary(24)
 
 
 
BioActivity Types:
Potency(111)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 118    Data Row: 126   Total Pages: 7   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26757102]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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2
[SID144211055]
Potency-Replicate_1 68.5199qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 - cell viability [AID651634, Type: confirmatory]
View
3
[SID144211055]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
4
[SID144211055]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
5
[SID144211055]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
6
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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7
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
View
8
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
9
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway - cell viability counter screen [AID743074, Type: confirmatory]
View
10
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway - cell viability counter screen [AID720693, Type: confirmatory]
View
11
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line - cell viability counter screen [AID743081, Type: confirmatory]
View
12
[SID144211055]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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13
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway - cell viability counter screen [AID743086, Type: confirmatory]
View
14
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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15
[SID144211055]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
View
16
[SID144211055]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
View
17
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
18
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
View
19
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
View
20
[SID144211055]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View