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Catechin (CID 9064) - Compound BioActivity Data
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BioActivity Outcomes:
Active(50)
 
 
Inactive(343)
 
 
Inconclusive(53)
 
 
Unspecified(135)
 
 
Top Targets:
prostaglandin..(11)
 
 
 
 
Tryp SPc(10)
 
 
 
 
7tm 4(9)
 
 
 
 
HELICc(6)
 
 
 
Tubulin-bindi..(5)
 
 
 
BioAssay Types:
Confirmatory(284)
 
 
 
 
 
Literature(193)
 
 
 
 
 
Screening(28)
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(205)
 
 
 
 
 
IC50(38)
 
 
 
 
 
EC50(15)
 
 
Kd(4)
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 514    Data Row: 581   Total Pages: 30   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123094711]
Ki 0.6Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate by Dixon reciprocal plot analysis [AID1066693, Type: Literature]Arginase [gi:74764753]
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2
[SID123094711]
IC50 1.61Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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3
[SID123094711]
IC50 1.7Inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate incubated for 10 mins prior to substrate addition measured after 10 mins by colorimetry [AID1066694, Type: Literature]Arginase [gi:74764753]
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4
[SID123094711]
IC50 2.31Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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5
[SID123094711]
ID50 2.75Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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6
[SID123094711]
ID50 2.86Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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7
[SID123094711]
IC50 2.9Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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8
[SID123094711]
IC50 4.1Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay [AID333439, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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9
[SID123094711]
IC50 4.3Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry [AID650645, Type: Literature]
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10
[SID90341637]
Potency 4.7444qHTS Validation Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1) [AID488816, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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11
[SID90341637]
Potency 4.7444qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). [AID588795, Type: confirmatory]flap endonuclease 1 [Homo sapiens] [gi:4758356]
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12
[SID123094711]
IC50 5.3Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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13
[SID208013757]
Kd 8.9Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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14
[SID208013757]
Kd 8.9Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB [AID977611, Type: Literature]
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15
[SID50105958]
Potency 11.2202qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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16
[SID50105958]
Potency 12.5893qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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17
[SID123094711]
IC50 13.1Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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18
[SID26753531]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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19
[SID123094711]
IC50 20.2Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay [AID333440, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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20
[SID123094711]
IC50 20.2Free radical scavenging activity of DPPH was determined; value taken from reference 11 [AID226690, Type: Literature]
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