| 1 | [SID99517168] | Active | EC50 | 1.129 | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators [AID493060, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] |  View X | Row No. | 1 | | Structure | 
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | EC50 | 1.129 [uM] | | BioAssay | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators | | AID | 493060 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 2 | [SID99517168] | Active | EC50 | 1.129 | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators [AID493060, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 2 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | EC50 | 1.129 [uM] | | BioAssay | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators | | AID | 493060 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 3 | [SID99517168] | Active | EC50 | 1.129 | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators [AID493060, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 3 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | EC50 | 1.129 [uM] | | BioAssay | Late stage results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for AHR activators | | AID | 493060 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 4 | [SID22414569] | Active | EC50 | 1.364 | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID463088, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 4 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | EC50 | 1.364 [uM] | | BioAssay | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 463088 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 5 | [SID22414569] | Active | EC50 | 1.364 | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID463088, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 5 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | EC50 | 1.364 [uM] | | BioAssay | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 463088 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 6 | [SID22414569] | Active | EC50 | 1.364 | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID463088, Type: confirmatory] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 6 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | EC50 | 1.364 [uM] | | BioAssay | Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 463088 | | BioAssay type | confirmatory | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 7 | [SID22414569] | Active | Potency | 1.6482 | qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 [AID2289, Type: confirmatory] | | View X | Row No. | 7 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | Potency | 1.6482 [uM] | | BioAssay | qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21 | | AID | 2289 | | BioAssay type | confirmatory | | Target | | | PubMed | | | Data Table | |
|
| 8 | [SID22414569] | Active | Potency | 2.8184 | qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory] | RAB9A gene product [Homo sapiens] [gi:4759012] | View X | Row No. | 8 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | Potency | 2.8184 [uM] | | BioAssay | qHTS Assay for Rab9 Promoter Activators | | AID | 485297 | | BioAssay type | confirmatory | | Target | RAB9A gene product [Homo sapiens] [gi:4759012] | | PubMed | | | Data Table | |
|
| 9 | [SID22414569] | Active | Potency | 3.5481 | qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory] | NPC1 gene product [Homo sapiens] [gi:255652944] | View X | Row No. | 9 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | Potency | 3.5481 [uM] | | BioAssay | qHTS Assay for NPC1 Promoter Activators | | AID | 485313 | | BioAssay type | confirmatory | | Target | NPC1 gene product [Homo sapiens] [gi:255652944] | | PubMed | | | Data Table | |
|
| 10 | [SID22414569] | Active | Potency | 11.2202 | qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory] | survival motor neuron protein isoform d [Homo sapiens] [gi:10937869] | View X | Row No. | 10 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | Potency | 11.2202 [uM] | | BioAssay | qHTS Assay for Enhancers of SMN2 Splice Variant Expression | | AID | 1458 | | BioAssay type | confirmatory | | Target | survival motor neuron protein isoform d [Homo sapiens] [gi:10937869] | | PubMed | | | Data Table | |
|
| 11 | [SID22414569] | Active | Potency | 11.2202 | qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory] | survival motor neuron protein isoform d [Homo sapiens] [gi:10937869] | View X | Row No. | 11 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | Potency | 11.2202 [uM] | | BioAssay | qHTS Assay for Enhancers of SMN2 Splice Variant Expression | | AID | 1458 | | BioAssay type | confirmatory | | Target | survival motor neuron protein isoform d [Homo sapiens] [gi:10937869] | | PubMed | | | Data Table | |
|
| 12 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression [AID602169, Type: other] | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | View X | Row No. | 12 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression | | AID | 602169 | | BioAssay type | other | | Target | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | | PubMed | | | Data Table | |
|
| 13 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression [AID602169, Type: other] | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | View X | Row No. | 13 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression | | AID | 602169 | | BioAssay type | other | | Target | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | | PubMed | | | Data Table | |
|
| 14 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression [AID602169, Type: other] | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | View X | Row No. | 14 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression | | AID | 602169 | | BioAssay type | other | | Target | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | | PubMed | | | Data Table | |
|
| 15 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression [AID602169, Type: other] | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | View X | Row No. | 15 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Ovarian Carcinoma (BG1Luc4E2) Cell-based assay to identify inhibitors of Estrogen Receptor-Dependent Gene Expression | | AID | 602169 | | BioAssay type | other | | Target | estrogen receptor isoform 1 [Homo sapiens] [gi:62821794] | | PubMed | | | Data Table | |
|
| 16 | [SID22414569] | Active | | | Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening] | shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299] | View X | Row No. | 16 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin | | AID | 2314 | | BioAssay type | screening | | Target | shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299] | | PubMed | | | Data Table | |
|
| 17 | [SID22414569] | Active | | | A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening] | shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299] | View X | Row No. | 17 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | A qHTS for Small Molecule Inhibitors of Shiga Toxin | | AID | 2315 | | BioAssay type | screening | | Target | shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299] | | PubMed | | | Data Table | |
|
| 18 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR [AID602171, Type: other] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 18 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR | | AID | 602171 | | BioAssay type | other | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 19 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR [AID602171, Type: other] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 19 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR | | AID | 602171 | | BioAssay type | other | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 20 | [SID99517168] | Active | | | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR [AID602171, Type: other] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 20 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Active | | BioAssay | Late stage assay provider counterscreen for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based Human Hepatoma (HG2L7.5c1) Cell-based assay to identify activators of AhR | | AID | 602171 | | BioAssay type | other | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 21 | [SID22414569] | Active | | | MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening] | | View X | Row No. | 21 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators | | AID | 1814 | | BioAssay type | screening | | Target | | | PubMed | | | Data Table | |
|
| 22 | [SID22414569] | Active | | | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID2845, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 22 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2845 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 23 | [SID22414569] | Active | | | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID2845, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 23 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2845 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 24 | [SID22414569] | Active | | | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) [AID2845, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 24 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based cell-based high throughput confirmation assay for activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2845 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 25 | [SID22414569] | Active | | | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 25 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2796 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 26 | [SID22414569] | Active | | | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 26 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2796 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 27 | [SID22414569] | Active | | | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) [AID2796, Type: screening] | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | View X | Row No. | 27 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Active | | BioAssay | Luminescence-based primary cell-based high throughput screening assay to identify activators of the Aryl Hydrocarbon Receptor (AHR) | | AID | 2796 | | BioAssay type | screening | | Target | aryl hydrocarbon receptor precursor [Homo sapiens] [gi:4502003] | | PubMed | | | Data Table | |
|
| 28 | [SID22414569] | Unspecified | Potency | | qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory] | acid sphingomyelinase [Homo sapiens] [gi:179095] | View X | Row No. | 28 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Unspecified | | Potency | [uM] | | BioAssay | qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate | | AID | 624178 | | BioAssay type | confirmatory | | Target | acid sphingomyelinase [Homo sapiens] [gi:179095] | | PubMed | | | Data Table | |
|
| 29 | [SID22414569] | Unspecified | Potency | | qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory] | acid sphingomyelinase [Homo sapiens] [gi:179095] | View X | Row No. | 29 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Unspecified | | Potency | [uM] | | BioAssay | qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate | | AID | 624178 | | BioAssay type | confirmatory | | Target | acid sphingomyelinase [Homo sapiens] [gi:179095] | | PubMed | | | Data Table | |
|
| 30 | [SID22414569] | Inactive | Potency | 1.6482 | qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 [AID2288, Type: confirmatory] | | View X | Row No. | 30 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | 1.6482 [uM] | | BioAssay | qHTS Assay for Modulators of miRNAs and/orActivators of miR-21 | | AID | 2288 | | BioAssay type | confirmatory | | Target | | | PubMed | | | Data Table | |
|
| 31 | [SID22414569] | Inactive | Potency | 9.285 | Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory] | | View X | Row No. | 31 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | 9.285 [uM] | | BioAssay | Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation | | AID | 504834 | | BioAssay type | confirmatory | | Target | | | PubMed | | | Data Table | |
|
| 32 | [SID22414569] | Inactive | Potency | 10.4179 | Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory] | | View X | Row No. | 32 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | 10.4179 [uM] | | BioAssay | Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation | | AID | 504832 | | BioAssay type | confirmatory | | Target | | | PubMed | | | Data Table | |
|
| 33 | [SID22414569] | Inactive | Potency | 32.6427 | A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory] | GMNN gene product [Homo sapiens] [gi:7705682] | View X | Row No. | 33 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | 32.6427 [uM] | | BioAssay | A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. | | AID | 624296 | | BioAssay type | confirmatory | | Target | GMNN gene product [Homo sapiens] [gi:7705682] | | PubMed | | | Data Table | |
|
| 34 | [SID22414569] | Inactive | EC50 | 115.965 | Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) [AID463086, Type: confirmatory] | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | View X | Row No. | 34 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | EC50 | 115.965 [uM] | | BioAssay | Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) | | AID | 463086 | | BioAssay type | confirmatory | | Target | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | | PubMed | | | Data Table | |
|
| 35 | [SID22414569] | Inactive | EC50 | 115.965 | Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) [AID463086, Type: confirmatory] | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | View X | Row No. | 35 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | EC50 | 115.965 [uM] | | BioAssay | Luminescence-based counterscreen for activators of the Aryl Hydrocarbon Receptor (AHR): cell-based high throughput dose response screening assay for activators of the Pregnane X Receptor (PXR) | | AID | 463086 | | BioAssay type | confirmatory | | Target | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | | PubMed | | | Data Table | |
|
| 36 | [SID99517168] | Inactive | EC50 | 116.135 | Late stage counterscreen results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for activators of the Pregnane X Receptor (PXR) [AID493061, Type: confirmatory] | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | View X | Row No. | 36 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Inactive | | EC50 | 116.135 [uM] | | BioAssay | Late stage counterscreen results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for activators of the Pregnane X Receptor (PXR) | | AID | 493061 | | BioAssay type | confirmatory | | Target | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | | PubMed | | | Data Table | |
|
| 37 | [SID99517168] | Inactive | EC50 | 116.135 | Late stage counterscreen results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for activators of the Pregnane X Receptor (PXR) [AID493061, Type: confirmatory] | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | View X | Row No. | 37 | | Structure |
| | Substance | | | SID | 99517168 | | CID | 901941 | | Outcome | Inactive | | EC50 | 116.135 [uM] | | BioAssay | Late stage counterscreen results for the probe development effort to identify activators of the Aryl Hydrocarbon Receptor (AHR): Luminescence-based cell-based dose response assay for activators of the Pregnane X Receptor (PXR) | | AID | 493061 | | BioAssay type | confirmatory | | Target | nuclear receptor subfamily 1 group I member 2 isoform 1 [Homo sapiens] [gi:34398348] | | PubMed | | | Data Table | |
|
| 38 | [SID22414569] | Inactive | | | uHTS identification of inhibitors of cullin neddylation in a TR-FRET assay [AID651699, Type: screening] | NAE1 gene product [Homo sapiens] [gi:4502169] | View X | Row No. | 38 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | uHTS identification of inhibitors of cullin neddylation in a TR-FRET assay | | AID | 651699 | | BioAssay type | screening | | Target | NAE1 gene product [Homo sapiens] [gi:4502169] | | PubMed | | | Data Table | |
|
| 39 | [SID22414569] | Inactive | | | TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide [AID686964, Type: screening] | Methyl-CpG binding domain protein 2 [Homo sapiens] [gi:21595776] | View X | Row No. | 39 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide | | AID | 686964 | | BioAssay type | screening | | Target | Methyl-CpG binding domain protein 2 [Homo sapiens] [gi:21595776] | | PubMed | | | Data Table | |
|
| 40 | [SID22414569] | Inactive | Potency | | qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463254, Type: confirmatory] | ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692] | View X | Row No. | 40 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | [uM] | | BioAssay | qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter | | AID | 463254 | | BioAssay type | confirmatory | | Target | ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692] | | PubMed | | | Data Table | |
|
| 41 | [SID22414569] | Inactive | Potency | | qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter [AID463254, Type: confirmatory] | ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692] | View X | Row No. | 41 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | [uM] | | BioAssay | qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter | | AID | 463254 | | BioAssay type | confirmatory | | Target | ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens] [gi:188528692] | | PubMed | | | Data Table | |
|
| 42 | [SID22414569] | Inactive | | | uHTS identification of small molecule activators of alpha dystroglycan glycosylation [AID624168, Type: screening] | LARGE [Homo sapiens] [gi:47678551] | View X | Row No. | 42 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | uHTS identification of small molecule activators of alpha dystroglycan glycosylation | | AID | 624168 | | BioAssay type | screening | | Target | LARGE [Homo sapiens] [gi:47678551] | | PubMed | | | Data Table | |
|
| 43 | [SID22414569] | Inactive | EC50 | | Image-based HTS for Selective Agonists of GPR55 [AID1961, Type: confirmatory] | G-protein coupled receptor 55 [Homo sapiens] [gi:33695107] | View X | Row No. | 43 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | EC50 | [uM] | | BioAssay | Image-based HTS for Selective Agonists of GPR55 | | AID | 1961 | | BioAssay type | confirmatory | | Target | G-protein coupled receptor 55 [Homo sapiens] [gi:33695107] | | PubMed | | | Data Table | |
|
| 44 | [SID22414569] | Inactive | IC50 | | Image-Based HTS for Selective Antagonists for GPR55 [AID2013, Type: confirmatory] | G-protein coupled receptor 55 [Homo sapiens] [gi:33695107] | View X | Row No. | 44 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | IC50 | [uM] | | BioAssay | Image-Based HTS for Selective Antagonists for GPR55 | | AID | 2013 | | BioAssay type | confirmatory | | Target | G-protein coupled receptor 55 [Homo sapiens] [gi:33695107] | | PubMed | | | Data Table | |
|
| 45 | [SID22414569] | Inactive | Potency | | A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory] | GMNN gene product [Homo sapiens] [gi:7705682] | View X | Row No. | 45 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | [uM] | | BioAssay | A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. | | AID | 624297 | | BioAssay type | confirmatory | | Target | GMNN gene product [Homo sapiens] [gi:7705682] | | PubMed | | | Data Table | |
|
| 46 | [SID22414569] | Inactive | | | Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) [AID602281, Type: screening] | ABHD5 gene product [Homo sapiens] [gi:31542303] | View X | Row No. | 46 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) | | AID | 602281 | | BioAssay type | screening | | Target | ABHD5 gene product [Homo sapiens] [gi:31542303] | | PubMed | | | Data Table | |
|
| 47 | [SID22414569] | Inactive | | | Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9 [AID488922, Type: screening] | KCNK9 gene product [Homo sapiens] [gi:7706135] | View X | Row No. | 47 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | Primary cell-based screen for identification of compounds that inhibit the two-pore domain potassium channel KCNK9 | | AID | 488922 | | BioAssay type | screening | | Target | KCNK9 gene product [Homo sapiens] [gi:7706135] | | PubMed | | | Data Table | |
|
| 48 | [SID125058919] | Inactive | | | A screen for small molecule inhibitors of the human deubiquitinating enzyme, UCH37 [AID588478, Type: other] | ubiquitin C-terminal hydrolase UCH37 [Homo sapiens] [gi:4877999] | View X | Row No. | 48 | | Structure |
| | Substance | | | SID | 125058919 | | CID | 901941 | | Outcome | Inactive | | BioAssay | A screen for small molecule inhibitors of the human deubiquitinating enzyme, UCH37 | | AID | 588478 | | BioAssay type | other | | Target | ubiquitin C-terminal hydrolase UCH37 [Homo sapiens] [gi:4877999] | | PubMed | | | Data Table | |
|
| 49 | [SID22414569] | Inactive | | | Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase Methylesterase 1 (PME-1). [AID2130, Type: screening] | protein phosphatase methylesterase 1 [Homo sapiens] [gi:7706645] | View X | Row No. | 49 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | BioAssay | Fluorescence polarization-based primary biochemical high throughput screening assay to identify inhibitors of Protein Phosphatase Methylesterase 1 (PME-1). | | AID | 2130 | | BioAssay type | screening | | Target | protein phosphatase methylesterase 1 [Homo sapiens] [gi:7706645] | | PubMed | | | Data Table | |
|
| 50 | [SID22414569] | Inactive | Potency | | qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory] | DNA polymerase kappa [Homo sapiens] [gi:7705344] | View X | Row No. | 50 | | Structure |
| | Substance | | | SID | 22414569 | | CID | 901941 | | Outcome | Inactive | | Potency | [uM] | | BioAssay | qHTS for Inhibitors of Polymerase Kappa | | AID | 588579 | | BioAssay type | confirmatory | | Target | DNA polymerase kappa [Homo sapiens] [gi:7705344] | | PubMed | | | Data Table | |
|
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
