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Inositol (CID 892) - Compound BioActivity Data
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BioActivity Outcomes:
Active(13)
 
 
Inactive(1770)
 
 
Inconclusive(18)
 
 
Unspecified(30)
 
 
Top Targets:
7TM GPCR Srx(57)
 
 
 
7TM GPCR Srsx(47)
 
 
NR LBD PPAR(16)
 
 
B zip1(16)
 
 
CAP ED(15)
 
 
BioAssay Types:
Screening(1028)
 
 
 
 
Confirmatory(570)
 
 
 
 
 
Literature(133)
 
 
 
 
 
Summary(48)
 
 
 
BioActivity Types:
Potency(511)
 
 
 
 
 
IC50(42)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 669    Data Row: 1831   Total Pages: 92   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136925215]
IC50 2Inhibition of Phosphoinositide specific phospholipase C (PI-PLC) from Bacillus cereus on the internal face of the cell membrane. [AID158606, Type: Literature]
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2
[SID104243012]
IC50 10Inhibition of Phosphoinositide specific phospholipase C (PI-PLC) from Bacillus cereus on the internal face of the cell membrane. [AID158606, Type: Literature]
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3
[SID144205195]
Potency 14.9631qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID53812881]
IC50 5700Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of The Trimeric Neck And Carbohydrate Recognition Domain Of Human Surfactant Protein D In Complex With Myoinositol [gi:149242688]
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5
[SID53812881]
IC50 5700Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Crystal Structure Of The Trimeric Neck And Carbohydrate Recognition Domain Of Human Surfactant Protein D In Complex With Myoinositol [gi:149242688]
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6
[SID53812881]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Crystal Structure Of The Trimeric Neck And Carbohydrate Recognition Domain Of Human Surfactant Protein D In Complex With Myoinositol [gi:149242688]
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7
[SID103622347]
Effect on amyloid beta 42 aggregation assessed as inhibition of fiber formation at 3 mM [AID361504, Type: Literature]
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8
[SID56324719]
Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_SinglePoint_HTS_Activity [AID504558, Type: screening]LMP1 [Human herpesvirus 4] [gi:23893668]
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9
[SID56320900]
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library [AID2557, Type: screening]integrin alpha-4 precursor [Homo sapiens] [gi:67191027]
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10
[SID56320900]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human M1 muscarinic receptor (CHRM1) [AID588852, Type: screening]muscarinic acetylcholine receptor M1 [Homo sapiens] [gi:37622910]
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11
[SID56320893]
HTS for Identification of VLA-4 Allosteric Modulators from MLPCN library [AID2557, Type: screening]integrin alpha-4 precursor [Homo sapiens] [gi:67191027]
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12
[SID73813]
NCI human tumor cell line growth inhibition assay. Data for the SNB-75 Central Nervous System cell line [AID55, Type: confirmatory]
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13
[SID48416105]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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14
[SID103622347]
IC50 100Inhibition of amyloid beta (1 to 42) aggregation (unknown origin) at 4:1 compound to protein concentration after 48 hrs by thioflavin T fluorescence assay [AID748709, Type: Literature]
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15
[SID103622347]
IC50 410Inhibition of Phosphoinositide specific phospholipase C (PI-PLC) from Bacillus cereus on the internal face of the cell membrane. [AID158606, Type: Literature]
View
16
[SID136925215]
IC50 475.7Inhibition of Baker's yeast Alpha-glucosidase-1 using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins prior substrate addition measured after 20 mins by spectrophotometry [AID647234, Type: Literature]
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17
[SID104243012]
Km 580Oxidation catalyzed by inositol dehydrogenase at pH 9.13. [AID27334, Type: Literature]
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18
[SID123092460]
IC50 1256.1Inhibition of Baker's yeast Alpha-glucosidase-1 using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins prior substrate addition measured after 20 mins by spectrophotometry [AID647234, Type: Literature]
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19
[SID104243012]
Ratio of Kcat to Km for Neisseria meningitidis lgtC [AID500279, Type: Literature]
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20
[SID104243012]
Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset [AID588209, Type: Literature]
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