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hexanoic acid (CID 8892) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(4)
 
 
Inactive(177)
 
 
Inconclusive(14)
 
 
Unspecified(27)
 
 
Top Targets:
NR LBD PPAR(16)
 
 
 
NR LBD AR(14)
 
 
NR LBD ER(14)
 
 
NR LBD GR(8)
 
 
NR LBD VDR(8)
 
 
 
BioAssay Types:
Confirmatory(124)
 
 
 
Summary(48)
 
 
 
Literature(27)
 
 
 
 
BioActivity Types:
Potency(160)
 
 
 
Ki(2)
 
 
IC50(2)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 136    Data Row: 222   Total Pages: 5   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176197]
IC50 0.0046Antitumor activity against mouse L1210 cells [AID406142, Type: Literature]
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2
[SID103176197]
Ki 9.12011Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr [AID360149, Type: Literature]Solute carrier family 22 member 20 [gi:56404586]
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3
[SID103176197]
Ki 37.1535Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr [AID360150, Type: Literature]Solute carrier family 22 member 6 [gi:81901833]
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4
[SID48415197]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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5
[SID103176197]
LD50 10Cytotoxicity against mouse RAW264.7 cells [AID627981, Type: Literature]
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6
[SID103176197]
IC50 68.2Inhibition of aldose reductase [AID309933, Type: Literature]
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7
[SID103176197]
Antibacterial activity against Bacillus subtilis ATCC 9372 after 2 days by broth dilution method [AID359935, Type: other]
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8
[SID103176197]
Antibacterial activity against Brevibacterium ammoniagenes ATCC 6872 after 2 days by broth dilution method [AID359936, Type: other]
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9
[SID103176197]
Antibacterial activity against Staphylococcus aureus ATCC 12598 after 2 days by broth dilution method [AID359937, Type: other]
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10
[SID103176197]
Antibacterial activity against Streptococcus mutans ATCC 125175 after 2 days by broth dilution method [AID359938, Type: other]
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11
[SID103176197]
Antibacterial activity against Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID359939, Type: other]
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12
[SID103176197]
Antibacterial activity against Escherichia coli ATCC 9637 after 2 days by broth dilution method [AID359940, Type: other]
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13
[SID103176197]
Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 2 days by broth dilution method [AID359941, Type: other]
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14
[SID103176197]
Antibacterial activity against Enterobacter aerogenes ATCC 13048 after 2 days by broth dilution method [AID359942, Type: other]
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15
[SID103176197]
Antifungal activity against Saccharomyces cerevisiae ATCC 7754 after 2 days by broth dilution method [AID359943, Type: other]
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16
[SID103176197]
Antifungal activity against Candida utilis ATCC 9226 after 2 days by broth dilution method [AID359944, Type: other]
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17
[SID103176197]
Antibacterial activity against Proteus vulgaris ATCC 13315 after 2 days by broth dilution method [AID359945, Type: other]
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18
[SID103176197]
Antifungal activity against Pityrosporum ovale ATCC 14521 after 3 days by broth dilution method [AID359946, Type: other]
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19
[SID103176197]
Antifungal activity against Penicillium chrysogenum ATCC 10106 after 5 days by broth dilution method [AID359947, Type: other]
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20
[SID103176197]
Antifungal activity against Trichophyton mentagrophytes ATCC 18748 after 5 days by broth dilution method [AID359948, Type: other]
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21
[SID103176197]
Ratio of pKi for mouse Oat1 expressed in Xenopus oocytes to pKi for mouse Oat6 expressed in Xenopus oocytes [AID360151, Type: Literature]
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22
[SID103176197]
Partition coefficient (logP) [AID23251, Type: Literature]
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23
[SID103176197]
Partition coefficient (logP) (benzene) [AID23252, Type: Literature]
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24
[SID103176197]
Partition coefficient (logP) (carbon tetrachloride) [AID23253, Type: Literature]
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25
[SID103176197]
Partition coefficient (logP) (chloroform) [AID23254, Type: Literature]
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26
[SID103176197]
Partition coefficient (logP) (ether) [AID23255, Type: Literature]
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27
[SID103176197]
Partition coefficient (logP) (hexane) [AID23256, Type: Literature]
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28
[SID103176197]
Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system [AID237685, Type: Literature]
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29
[SID103176197]
Specific activity of expressed human recombinant UGT1A10 [AID624613, Type: Literature]UDP-glucuronosyltransferase 1-10 [gi:29839636]
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30
[SID103176197]
Specific activity of expressed human recombinant UGT1A8 [AID624611, Type: Literature]UDP-glucuronosyltransferase 1-8 [gi:29839637]
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31
[SID103176197]
Cytotoxicity against mouse RAW264.7 cells at 5 uM [AID627980, Type: Literature]
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32
[SID144208715]
Potency-Replicate_1 9.6984qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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33
[SID144210724]
Potency-Replicate_1 27.306qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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34
[SID144210724]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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35
[SID144208715]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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36
[SID144208715]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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37
[SID144208715]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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38
[SID144208715]
Ratio Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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39
[SID144208715]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
40
[SID144208715]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
41
[SID144208715]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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42
[SID144208715]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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43
[SID144208715]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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44
[SID144210724]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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45
[SID144210724]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
46
[SID144210724]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
47
[SID144210724]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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48
[SID144210724]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
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49
[SID144210724]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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50
[SID144210724]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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