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4-(Chloroacetyl)acetanilide (CID 8805) - Compound BioActivity Data
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BioActivity Outcomes:
Active(235)
 
 
Inactive(546)
 
 
Inconclusive(172)
 
 
Unspecified(5)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(18)
 
 
 
 
7TM GPCR Srx(18)
 
 
7TM GPCR Srsx(15)
 
 
BioAssay Types:
Confirmatory(413)
 
 
 
 
 
Screening(292)
 
 
 
Summary(48)
 
 
 
 
Literature(6)
 
 
 
BioActivity Types:
Potency(402)
 
 
 
 
 
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 623    Data Row: 958   Total Pages: 20   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389974]
Potency 0.0447qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID85147160]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID144213271]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144213271]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144213271]
Potency-Replicate_1 1.9331qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID85147160]
Potency 2.0596qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID17389974]
Potency 3.1623Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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8
[SID144213271]
Potency-Replicate_1 3.89qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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9
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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10
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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11
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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12
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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13
[SID17389974]
Potency 4.4668qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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14
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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15
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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16
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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17
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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18
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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19
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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20
[SID85147160]
Potency 5.3233qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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21
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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22
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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23
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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24
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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25
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-013 [AID970, Type: confirmatory]
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26
[SID17389974]
Potency 6.3096Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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27
[SID144213271]
Potency-Replicate_1 6.859qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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28
[SID144213271]
Potency-Replicate_1 7.6959qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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29
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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30
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-002 [AID977, Type: confirmatory]
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31
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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32
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-016 [AID984, Type: confirmatory]
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33
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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34
[SID17389974]
Potency 7.9433Cell Viability - LYMP2-026 [AID989, Type: confirmatory]
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35
[SID144213271]
Potency-Replicate_1 8.6349qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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36
[SID17389974]
Potency 9.4392qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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37
[SID17389974]
Potency 10Cell Viability - LYMP2-006 [AID978, Type: confirmatory]
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38
[SID17389974]
Potency 10Cell Viability - LYMP2-025 [AID976, Type: confirmatory]
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39
[SID85147160]
Potency 10qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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40
[SID85147160]
Potency 12.5893qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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41
[SID17389974]
Potency 12.5893qHTS Assay for Anthrax Lethal Toxin Internalization [AID912, Type: confirmatory]lethal factor [Bacillus anthracis str. A2012] [gi:21392848]
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42
[SID17389974]
Potency 12.5893MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells [AID955, Type: confirmatory]
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43
[SID144213271]
Potency-Replicate_1 13.8022qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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44
[SID17389974]
Potency 15.8489MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Dead Cells [AID960, Type: confirmatory]
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45
[SID144213271]
Ratio Potency (uM) 17.376qHTS assay for small molecule activators of the heat shock response signaling pathway: Summary [AID743228, Type: summary]heat shock protein beta-1 [Homo sapiens] [gi:4504517]
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46
[SID17389974]
Potency-Replicate_1 18.8336qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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47
[SID144213271]
Potency-Replicate_1 19.3312qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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48
[SID17389974]
Potency 19.9526MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Live Cells [AID947, Type: confirmatory]
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49
[SID17389974]
Potency 22.3872qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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50
[SID144213271]
Potency-Replicate_1 24.3365qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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