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140-49-8 (CID 8805) - Compound BioActivity Data
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BioActivity Outcomes:
Active(234)
 
 
Inactive(558)
 
 
Inconclusive(169)
 
 
Unspecified(5)
 
 
Top Targets:
7tm 4(34)
 
 
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
 
 
NR LBD AR(18)
 
 
 
 
NR LBD TR(14)
 
 
 
 
BioAssay Types:
Confirmatory(413)
 
 
 
 
 
Screening(293)
 
 
 
Summary(48)
 
 
 
 
Literature(13)
 
 
 
BioActivity Types:
Potency(403)
 
 
 
 
 
IC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 624    Data Row: 966   Total Pages: 49   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389974]
Potency 0.0447qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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2
[SID85147160]
Potency 1.4581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID144213271]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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4
[SID144213271]
Potency-Replicate_1 1.7229qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144213271]
Potency-Replicate_1 1.9331qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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6
[SID85147160]
Potency 2.0596qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID17389974]
Potency 3.1623Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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8
[SID144213271]
Potency-Replicate_1 3.89qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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9
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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10
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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11
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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12
[SID17389974]
Potency 3.9811Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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13
[SID17389974]
Potency 4.4668qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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14
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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15
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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16
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-015 [AID971, Type: confirmatory]
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17
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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18
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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19
[SID17389974]
Potency 5.0119Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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20
[SID85147160]
Potency 5.3233qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen [AID720504, Type: confirmatory]serine/threonine-protein kinase PLK1 [Homo sapiens] [gi:21359873]
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