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5-chloroindole (CID 87110) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inconclusive(1)
 
 
Unspecified(3)
 
 
Top Targets:
M1 LTA4H(2)
 
 
BioAssay Types:
Literature(6)
 
 
 
 
BioActivity Types:
IC50(5)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID170482138]
IC50 1510Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Leukotriene A4 Hydrolase In Complex With Fragment 5- Chloroindole And Bestatin [gi:254839300]
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2
[SID170482138]
IC50 1510Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Leukotriene A4 Hydrolase In Complex With Fragment 5- Chloroindole And Bestatin [gi:254839300]
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3
[SID103687605]
IC50 1000Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE [AID420374, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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4
[SID103687605]
IC50 1510Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupole mass spectrometry [AID420375, Type: Literature]Leukotriene A-4 hydrolase [gi:126353]
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5
[SID103687605]
Solubility in methanol [AID420373, Type: Literature]
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6
[SID103687605]
IC50 Inhibition of ionomycin-stimulated LTB4 production in human whole blood treated 15 mins prior to ionomycin challenge measured after 30 mins of stimulation by enzyme-linked immunosorbent assay [AID420376, Type: Literature]
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