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benzil (CID 8651) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(34)
 
 
Inactive(88)
 
 
Inconclusive(9)
 
 
Unspecified(20)
 
 
Top Targets:
Esterase lipa..(35)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
NR LBD Fxr(4)
 
 
BioAssay Types:
Confirmatory(62)
 
 
 
Literature(54)
 
 
 
Summary(24)
 
 
 
BioActivity Types:
Potency(80)
 
 
 
Ki(34)
 
 
 
IC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 149    Data Row: 151   Total Pages: 8   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103460170]
Ki 0.0069Inhibition constant against human liver carboxylesterase 1 using 4-MUA (4-methylumbelliferone acetate) [AID239005, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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2
[SID103460170]
Ki 0.0136Inhibition constant against rabbit liver carboxylesterase using 4-MUA (4-methylumbelliferone acetate) [AID238980, Type: Literature]
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3
[SID103460170]
Ki 0.0147Inhibition constant against human intestinal carboxylesterase 2 (hiCE) using nitrophenyl acetate (o-NPA) as substrate [AID239272, Type: Literature]Cocaine esterase [gi:46576349]
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4
[SID103460170]
Ki 0.0147Inhibition constant against human intestinal carboxylesterase 2 (hiCE) using o-NPA (nitrophenyl acetate) as substrate [AID239273, Type: Literature]Cocaine esterase [gi:46576349]
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5
[SID103460170]
Ki 0.0147Inhibition constant against human intestinal carboxylesterase (hiCE) expressed in Sf21 cells using 3 mM o-NPA [AID239717, Type: Literature]Cocaine esterase [gi:46576349]
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6
[SID103460170]
Ki 0.01479Inhibition of human intestinal carboxylesterase [AID412227, Type: Literature]
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7
[SID103460170]
Ki 0.015Inhibition of human liver carboxylesterase1 using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry [AID612130, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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8
[SID103460170]
Ki 0.015Inhibition of human iCE using o-NPA as substrate by spectrophotometric assay [AID731514, Type: Literature]Cocaine esterase [gi:46576349]
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9
[SID103460170]
Ki 0.0151Inhibition of human intestinal carboxylesterase [AID295501, Type: Literature]Cocaine esterase [gi:46576349]
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10
[SID103460170]
IC50 0.019Inhibition of rabbit liver carboxylesterase after 5 mins [AID316371, Type: Literature]
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11
[SID103460170]
Ki 0.024Inhibition constant against human intestinal carboxylesterase 2 using 4-MUA (4-methylumbelliferone acetate) as substrate [AID239314, Type: Literature]Cocaine esterase [gi:46576349]
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12
[SID103460170]
IC50 0.027Inhibition of human recombinant carboxylesterase 1 after 5 mins [AID316365, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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13
[SID103460170]
IC50 0.029Inhibition of rabbit liver carboxylesterase after 15 mins [AID316372, Type: Literature]
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14
[SID103460170]
IC50 0.038Inhibition of human recombinant carboxylesterase 2 after 5 mins [AID316367, Type: Literature]Cocaine esterase [gi:46576349]
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15
[SID103460170]
IC50 0.043Inhibition of human recombinant carboxylesterase 1 after 15 mins [AID316366, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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16
[SID103460170]
IC50 0.044Inhibition of human recombinant carboxylesterase 2 after 15 mins [AID316368, Type: Literature]Cocaine esterase [gi:46576349]
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17
[SID103460170]
Ki 0.04467Inhibition of human carboxylesterase 1 [AID412228, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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18
[SID103460170]
Ki 0.045Inhibition of human intestinal carboxylesterase using o-nitrophenyl acetate as substrate after 5 mins by spectrophotometry [AID612131, Type: Literature]Cocaine esterase [gi:46576349]
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19
[SID103460170]
Ki 0.045Inhibition of human CE1 using o-NPA as substrate by spectrophotometric assay [AID731515, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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20
[SID103460170]
Ki 0.0451Inhibition of human carboxylesterase 1 [AID295502, Type: Literature]Liver carboxylesterase 1 [gi:119576]
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