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BioActivity Data for Compound fludioxonil (CID 86398)

BioActivity Outcomes:
Active(36)
 
 
Inactive(65)
 
 
Inconclusive(47)
 
 
Unspecified(111)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
 
BioAssay Types:
Literature(118)
 
 
 
 
Confirmatory(103)
 
 
 
 
Summary(29)
 
 
 
 
BioAssay Categories:
In vivo(5)
 
 
Toxicity(27)
 
 
 
 
 
ADME(54)
 
 
BioActivity Types:
Potency(126)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 251    Data Row: 259   Total Pages: 13   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211366]
Ratio Potency (uM) 1.1391qHTS assay to identify small molecule agonists of the RXR signaling pathway: Summary [AID1159531, Type: summary]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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2
[SID144211366]
Potency-Replicate_1 1.3801qHTS assay to identify small molecule agonists of the RXR signaling pathway [AID1159527, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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3
[SID144211366]
Potency-Replicate_1 2.169qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID26757296]
Potency 2.2387qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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5
[SID144211366]
Potency-Replicate_1 5.4483qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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6
[SID144211366]
AhR Potency (uM) 6.35221qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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7
[SID144211366]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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8
[SID144211366]
Potency-Replicate_1 8.6349qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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9
[SID144211366]
Ratio Potency (uM) 8.97274qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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10
[SID144211366]
Potency-Replicate_1 9.77qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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11
[SID144211366]
Ratio Potency (uM) 10.9649qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144211366]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID144211366]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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14
[SID144211366]
Potency-Replicate_1 12.2998qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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15
[SID144211366]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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16
[SID144211366]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
17
[SID144211366]
Ratio Potency (uM) 13.8006qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
18
[SID144211366]
Potency-Replicate_1 13.8006qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144211366]
Potency-Replicate_1 17.2289qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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20
[SID144211366]
Potency-Replicate_1 17.3739qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View