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fludioxonil (CID 86398) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(32)
 
 
Inactive(51)
 
 
Inconclusive(46)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Summary(24)
 
 
 
 
Literature(12)
 
 
 
BioActivity Types:
Potency(111)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 130    Data Row: 138   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211366]
Potency-Replicate_1 2.169qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID26757296]
Potency 2.2387qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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3
[SID144211366]
Potency-Replicate_1 5.4483qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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4
[SID144211366]
AhR Potency (uM) 6.35221qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144211366]
Potency-Replicate_1 7.6959qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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6
[SID144211366]
Potency-Replicate_1 8.6349qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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7
[SID144211366]
Potency-Replicate_1 8.6349qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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8
[SID144211366]
Ratio Potency (uM) 8.97274qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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9
[SID144211366]
Ratio Potency (uM) 10.9649qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743077, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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10
[SID144211366]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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11
[SID144211366]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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12
[SID144211366]
Potency-Replicate_1 12.2998qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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13
[SID144211366]
Potency-Replicate_1 12.2998qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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14
[SID144211366]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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15
[SID144211366]
Potency-Replicate_1 13.6854qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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16
[SID144211366]
Ratio Potency (uM) 13.8006qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway: Summary [AID743078, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
17
[SID144211366]
Potency-Replicate_1 13.8006qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
18
[SID144211366]
Potency-Replicate_1 17.3739qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID26757296]
Potency 17.7828qHTS assay for small molecule antagonists of androgen receptor signaling [AID588516, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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20
[SID144211366]
Potency-Replicate_1 27.306qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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21
[SID144211366]
AR Potency (uM) 29.4844qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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22
[SID144211366]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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23
[SID26757296]
Potency 31.6228qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling [AID588537, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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24
[SID144211366]
ER Potency (uM) 40.0798qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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25
[SID144211366]
Potency-Replicate_1 48.5577qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
26
[SID144211366]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
27
[SID144211366]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
28
[SID144211366]
qHTS assay to identify aromatase inhibitors: Summary [AID743139, Type: summary]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
View
29
[SID103583412]
Induction of GFP tagged PagsA expression in Aspergillus niger JvD1.1 at 104.2 ug/mL by fluorescence microscopy [AID386133, Type: Literature]
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30
[SID103583412]
Induction of GFP tagged PagsA-H2B expression in Aspergillus niger RD6.47 at 104.2 ug/mL by fluorescence microscopy [AID386134, Type: Literature]
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31
[SID103583412]
Antifungal activity against Aspergillus niger JvD1.1 at 104.2 ug/mL by microtiter plate [AID386135, Type: Literature]
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32
[SID103583412]
Antifungal activity against Aspergillus niger RD6.47 at 104.2 ug/mL by microtiter plate [AID386136, Type: Literature]
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33
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2 in SD/-Ura medium after 48 hrs by CLSI susceptibility test [AID417301, Type: Literature]
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34
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-HIK1 in SD/-Ura medium after 48 hrs by CLSI susceptibility test [AID417419, Type: Literature]
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35
[SID26757296]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
36
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-hik1-H736V in SD/-Ura medium after 48 hrs by CLSI susceptibility test [AID417420, Type: Literature]
View
37
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-hik1-D1153E in SD/-Ura medium after 48 hrs by CLSI susceptibility test [AID417421, Type: Literature]
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38
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2 in SG/-Ura medium after 48 hrs by CLSI susceptibility test [AID417422, Type: Literature]
View
39
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-HIK1 in SG/-Ura medium after 48 hrs by CLSI susceptibility test [AID417423, Type: Literature]
View
40
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-hik1-H736V in SG/-Ura medium after 48 hrs by CLSI susceptibility test [AID417424, Type: Literature]
View
41
[SID103583412]
Antifungal activity against Saccharomyces cerevisiae ATCC 201388 carrying pYES2-hik1-D1153E in SG/-Ura medium after 48 hrs by CLSI susceptibility test [AID417425, Type: Literature]
View
42
[SID144211366]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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43
[SID26757296]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
View
44
[SID26757296]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_5, Type: other]
View
45
[SID26757296]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
View
46
[SID26757296]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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47
[SID26757296]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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48
[SID26757296]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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49
[SID144211366]
Potency-Replicate_1 qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
View
50
[SID144211366]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
View