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difenoconazole (CID 86173) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(35)
 
 
Inactive(38)
 
 
Inconclusive(52)
 
 
Unspecified(12)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(9)
 
 
 
 
NR LBD ER(9)
 
 
 
NR LBD TR(7)
 
 
 
 
NR LBD Fxr(6)
 
 
 
 
BioAssay Types:
Confirmatory(93)
 
 
 
 
Summary(24)
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(111)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 129    Data Row: 137   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144211427]
Potency-Replicate_1 0.6859qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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2
[SID144211427]
Potency-Replicate_1 1.3685qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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3
[SID144211427]
Ratio Potency (uM) 2.00875qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway: Summary [AID743219, Type: summary]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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4
[SID144211427]
Potency-Replicate_1 2.4337qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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5
[SID144211427]
Potency-Replicate_1 2.4337qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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6
[SID144211427]
ER Potency (uM) 11.296qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID144211427]
Potency-Replicate_1 12.1972qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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8
[SID144211427]
Potency-Replicate_1 13.6854qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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9
[SID144211427]
Potency-Replicate_1 13.6854qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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10
[SID26757307]
Potency 15.3553qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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11
[SID144211427]
AR Potency (uM) 15.3553qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line: Summary [AID743054, Type: summary]AR protein [Homo sapiens] [gi:124375976]
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12
[SID144211427]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743221, Type: confirmatory]
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13
[SID144211427]
Potency-Replicate_1 21.8724qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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14
[SID144211427]
Potency-Replicate_1 30.6379qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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15
[SID26757307]
Potency 39.8107qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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16
[SID144211427]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway [AID720692, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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17
[SID26757307]
Potency 44.6684qHTS assay for small molecule antagonists of farnesoid X receptor signaling [AID588526, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
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18
[SID144211427]
Potency-Replicate_1 48.5577qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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19
[SID144211427]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway - cell viability counter screen [AID743194, Type: confirmatory]
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20
[SID144211427]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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21
[SID144211427]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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22
[SID144211427]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway - cell viability counter screen [AID743218, Type: confirmatory]
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23
[SID144211427]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
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24
[SID144211427]
Potency-Replicate_1 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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25
[SID144211427]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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26
[SID144211427]
Potency-Replicate_1 54.941qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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27
[SID144211427]
Potency-Replicate_1 61.1306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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28
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_7, Type: other]
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29
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_8, Type: other]
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30
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_1, Type: other]
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31
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_2, Type: other]
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32
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_3, Type: other]
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33
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_4, Type: other]
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34
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838_6, Type: other]
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35
[SID144211427]
qHTS assay to identify small molecule antagonists of the glucocorticoid receptor (GR) signaling pathway: Summary [AID720725, Type: summary]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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36
[SID103614011]
Antifungal activity against Rhizoctonia solani assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644735, Type: Literature]
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37
[SID103614011]
Antifungal activity against Botryotinia fuckeliana assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644736, Type: Literature]
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38
[SID103614011]
Antifungal activity against Alternaria solani assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644737, Type: Literature]
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39
[SID103614011]
Antifungal activity against Alternaria alternata Keissler assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644738, Type: Literature]
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40
[SID103614011]
Antifungal activity against Colletotrichum orbiculare assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644739, Type: Literature]
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41
[SID26757307]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
42
[SID103614011]
Fungicidal activity against Gibberella zeae assessed as inhibition of mycelium growth at 50 mg/L after 72 hrs [AID352271, Type: Literature]
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43
[SID103614011]
Fungicidal activity against Alternaria solani assessed as inhibition of mycelium growth at 50 mg/L after 72 hrs [AID352272, Type: Literature]
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44
[SID103614011]
Fungicidal activity against Cercospora arachidicola assessed as inhibition of mycelium growth at 50 mg/L after 72 hrs [AID352273, Type: Literature]
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45
[SID103614011]
Fungicidal activity against Physalospora pyricola assessed as inhibition of mycelium growth at 50 mg/L after 72 hrs [AID352274, Type: Literature]
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46
[SID103614011]
Fungicidal activity against Cladosporium cucumerinum assessed as inhibition of mycelium growth at 50 mg/L after 72 hrs [AID352275, Type: Literature]
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47
[SID103614011]
Antifungal activity against Gibberella zeae assessed as inhibition of mycelium growth at 100 ug/ml after 48 hrs [AID644734, Type: Literature]
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48
[SID144211427]
Potency-Replicate_1 4.8558qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
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49
[SID26757307]
Potency qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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50
[SID26757307]
Potency qHTS assay for small molecule agonists of glucocorticoid receptor signaling [AID588532, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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