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BioActivity Data for Compound dimethyl phthalate (CID 8554)

BioActivity Outcomes:
Inactive(460)
 
 
Inconclusive(26)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD TR(17)
 
 
NR LBD GR(16)
 
 
 
BioAssay Types:
Confirmatory(385)
 
 
 
Summary(69)
 
 
 
Literature(11)
 
 
 
 
Screening(6)
 
 
BioAssay Categories:
Biochemical(3)
 
 
 
Toxicity(57)
 
 
 
 
ADME(3)
 
 
Cell-based(13)
 
 
BioActivity Types:
Potency(394)
 
 
 
IC50(12)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 287    Data Row: 495   Total Pages: 25   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103317984]
IC50 100Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen. [AID64209, Type: Literature]
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2
[SID103317984]
IC50 100Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen. [AID203948, Type: Literature]
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3
[SID103317984]
Partition coefficient, log P by shake flask method [AID460407, Type: Literature]
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4
[SID103317984]
Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA [AID288184, Type: Literature]
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5
[SID103317984]
Permeability coefficient through artificial membrane in presence of stirred water layer [AID288185, Type: Literature]
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6
[SID103317984]
Membrane retention in permeability experiment with artificial membrane [AID288191, Type: Literature]
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7
[SID103317984]
Partition coefficient, log P of the compound [AID288192, Type: Literature]
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8
[SID17389503]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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9
[SID144207085]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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10
[SID144211362]
Potency-Replicate_1 0.0386qHTS assay to identify small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID1159521, Type: confirmatory]RAR-related orphan receptor gamma [Mus musculus] [gi:15928672]
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11
[SID144211362]
Potency-Replicate_1 1.0965qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID225144196]
IC50 10VEGF stimulated ADSC/ECFC co-culture nuclear area decrease (viability)-IC50 [AID1117324, Type: confirmatory]
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13
[SID225144196]
IC50 10VEGF stimulated ADSC/ECFC co-culture CD31-stained tube area decrease-IC50 [AID1117337, Type: confirmatory]
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14
[SID225144196]
IC50 20SW480 viability from Cell TiterGlo-IC50 [AID1117338, Type: confirmatory]
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15
[SID225144196]
IC50 20GSK3B-pretreated HCT116 viability from Cell TiterGlo-IC50 [AID1117339, Type: confirmatory]
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16
[SID225144196]
IC50 20HT-29 viability from Cell TiterGlo-IC50 [AID1117330, Type: confirmatory]
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17
[SID225144196]
IC50 20HCT116 viability from Cell TiterGlo-IC50 [AID1117332, Type: confirmatory]
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18
[SID225144196]
IC50 20Colo320 viability from Cell TiterGlo-IC50 [AID1117334, Type: confirmatory]
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19
[SID225144196]
IC50 20RKO viability from Cell TiterGlo-IC50 [AID1117322, Type: confirmatory]
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20
[SID225144196]
IC50 20SNU-C1 viability from Cell TiterGlo-IC50 [AID1117323, Type: confirmatory]
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