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dimethyl phthalate (CID 8554) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(426)
 
 
Inconclusive(25)
 
 
Unspecified(9)
 
 
Top Targets:
NR LBD PPAR(28)
 
 
 
NR LBD AR(25)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD TR(17)
 
 
NR LBD GR(16)
 
 
 
BioAssay Types:
Confirmatory(359)
 
 
 
Summary(63)
 
 
 
Literature(11)
 
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(372)
 
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 263    Data Row: 460   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103317984]
IC50 100Inhibition of [3H]WIN-35428 binding to the dopamine transporter in cynomolgus (macaca fascicularis) monkey caudate putamen. [AID64209, Type: Literature]
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2
[SID103317984]
IC50 100Inhibition of [3H]citalopram binding to the serotonin transporter in cynomolgus (macaca fascicularis) monkey caudate putamen. [AID203948, Type: Literature]
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3
[SID103317984]
Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA [AID288184, Type: Literature]
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4
[SID103317984]
Permeability coefficient through artificial membrane in presence of stirred water layer [AID288185, Type: Literature]
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5
[SID103317984]
Membrane retention in permeability experiment with artificial membrane [AID288191, Type: Literature]
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6
[SID103317984]
Partition coefficient, log P of the compound [AID288192, Type: Literature]
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7
[SID103317984]
Partition coefficient, log P by shake flask method [AID460407, Type: Literature]
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8
[SID17389503]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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9
[SID144207085]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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10
[SID144211362]
Potency-Replicate_1 1.0965qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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11
[SID144209343]
Potency-Replicate_1 22.0063qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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12
[SID144209343]
Potency-Replicate_1 27.4727qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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13
[SID144209343]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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14
[SID144211362]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
15
[SID144211362]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
16
[SID144211362]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
17
[SID144207085]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
18
[SID144207085]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
19
[SID144207085]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
20
[SID144209343]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View