ST50021501 (CID 847035) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(38)
 
 
Inactive(697)
 
 
Inconclusive(30)
 
 
Unspecified(2)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
alkPPc(14)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(10)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(500)
 
 
 
 
 
Confirmatory(242)
 
 
 
 
 
Literature(5)
 
 
BioActivity Types:
Potency(152)
 
 
 
 
 
IC50(47)
 
 
 
EC50(13)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 767    Data Row: 767   Total Pages: 16   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID4256670]
Potency 0.5802qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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2
[SID4256670]
Potency 1.122qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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3
[SID4256670]
Potency 2.5918qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
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4
[SID4256670]
Potency 2.8184qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]RAB9A gene product [Homo sapiens] [gi:4759012]
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5
[SID4256670]
Potency 3.1623qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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6
[SID4256670]
Potency 3.1623qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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7
[SID4256670]
Potency 3.9811qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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8
[SID4256670]
Potency 3.9811qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
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9
[SID131341905]
IC50 4.71A Cell-Based Counter Screen testing Compounds that Inhibit VEEV TC-83, in strain KU V3526 [AID602242, Type: confirmatory]
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10
[SID4256670]
IC50 6.38A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 [AID588727, Type: confirmatory]
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11
[SID131341905]
IC50 7.09A Cell-Based Confirmatory Screen for Compounds that Inhibit VEEV, TC-83 (2) [AID602241, Type: confirmatory]
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12
[SID4256670]
Potency 8.9125High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment: Confirmation of PNC Inhibition [AID2730, Type: confirmatory]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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13
[SID4256670]
IC50 10A Cell Based HTS Approach for the Discovery of New Inhibitors of Respiratory syncytial virus (RSV) [AID2391, Type: confirmatory]
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14
[SID4256670]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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15
[SID4256670]
Potency 12.5893qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
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16
[SID4256670]
Potency 16.9441qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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17
[SID4256670]
CC50 17.19An HTS Cytotoxicity Screen to evaluate New Inhibitors of Respiratory Syncytial Virus (RSV) [AID2410, Type: confirmatory]
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18
[SID4256670]
EC50 20.207Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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19
[SID4256670]
EC50 20.207Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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20
[SID4256670]
EC50 20.207Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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21
[SID4256670]
EC50 20.207Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response [AID1241, Type: confirmatory]NFKB1 gene product [Homo sapiens] [gi:34577122]
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22
[SID4256670]
CC50 25Vero 76 Cytoxicity Assay for VEEV Compounds [AID588719, Type: confirmatory]
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23
[SID131341905]
CC50 50Vero 76 Cytoxicity Assay for VEEV Compounds (2) [AID602240, Type: confirmatory]
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24
[SID4256670]
EC50 50A cytotoxicity screen of small molecule inhibitors of the PhoP regulon in Salmonella typhimurium identified in the primary screen [AID2253, Type: confirmatory]
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25
[SID4256670]
 Modulators of Post-Golgi Transport [AID739, Type: screening]
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26
[SID4256670]
 MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - activators [AID1814, Type: screening]
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27
[SID4256670]
 Non-Nucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity HTS Single Point (MLSMR Library) [AID841, Type: screening]
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28
[SID4256670]
 Primary HTS assay for chemical inhibitors of antigen receptor-induced NF-kappaB activation [AID465, Type: screening]
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29
[SID4256670]
 Dose-response cell-based assay for chemical inhibitors of antigen receptor-induced NF-kappaB activation [AID586, Type: confirmatory]
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30
[SID4256670]
 Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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31
[SID4256670]
AbsAC40_uM Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_Dose_CherryPick_Activity [AID651717, Type: confirmatory]
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32
[SID4256670]
 Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay [AID504607, Type: screening]
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33
[SID4256670]
 Counterscreen of compound fluorescence effects on High-throughput multiplex microsphere screening for inhibitors of toxin protease [AID624483, Type: screening]
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34
[SID131341905]
 Virus Titer Reduction Secondary Screen for Compounds that Inhibit VEEV (TC-83 strain) [AID602307, Type: other]
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35
[SID4256670]
 Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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36
[SID4256670]
 Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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37
[SID4256670]
 Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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38
[SID4256670]
 A qHTS for Small Molecule Inhibitors of Shiga Toxin [AID2315, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
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39
[SID4256670]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
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40
[SID4256670]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
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41
[SID4256670]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
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42
[SID4256670]
 High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Primary Screen [AID1239, Type: screening]NFKB1 gene product [Homo sapiens] [gi:34577122]
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43
[SID4256670]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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44
[SID4256670]
 uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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45
[SID4256670]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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46
[SID4256670]
 Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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47
[SID4256670]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
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48
[SID4256670]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
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49
[SID4256670]
 Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 MEK Kinase3 Wildtype [AID1529, Type: screening]mitogen-activated protein kinase kinase kinase 3 isoform 1 [Homo sapiens] [gi:42794767]
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50
[SID4256670]
 High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment [AID2417, Type: screening]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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