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BioActivity Data for Compound 2,4-dinitrotoluene (CID 8461)

BioActivity Outcomes:
Active(14)
 
 
Inactive(392)
 
 
Inconclusive(16)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD ER(18)
 
 
NR LBD AR(18)
 
 
 
NR LBD TR(14)
 
 
 
NR LBD VDR(12)
 
 
BioAssay Types:
Confirmatory(325)
 
 
 
 
Summary(56)
 
 
 
Literature(3)
 
 
 
BioAssay Categories:
Toxicity(52)
 
 
 
 
BioActivity Types:
Potency(333)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 262    Data Row: 425   Total Pages: 22   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210811]
Potency-Replicate_1 19.4938qHTS assay to identify small molecule agonists of the RXR signaling pathway [AID1159527, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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2
[SID26753101]
Potency 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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3
[SID144208982]
Potency-Replicate_1 60.2613qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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5
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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6
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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7
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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8
[SID48413682]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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9
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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10
[SID48413680]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
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11
[SID48415159]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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12
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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13
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
14
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
15
[SID17389585]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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16
[SID103567994]
Anticarcinogenic activity in rat assessed as induction of tumors per day [AID318681, Type: Literature]
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17
[SID26753101]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
18
[SID144210811]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free culture [AID720683, Type: confirmatory]
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19
[SID144210811]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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20
[SID144208982]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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