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2,4-dinitrotoluene (CID 8461) - Compound BioActivity Data
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BioActivity Outcomes:
Active(14)
 
 
Inactive(349)
 
 
Inconclusive(30)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD AR(18)
 
 
 
NR LBD ER(18)
 
 
NR LBD TR(14)
 
 
 
NR LBD Fxr(12)
 
 
 
BioAssay Types:
Confirmatory(305)
 
 
 
 
Summary(48)
 
 
 
Literature(2)
 
 
 
BioActivity Types:
Potency(304)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 248    Data Row: 396   Total Pages: 8   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID26753101]
Potency 54.4827qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
2
[SID144208982]
Potency-Replicate_1 60.2613qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
3
[SID144208982]
Potency-Replicate_1 60.2613qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
4
[SID48413680]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
5
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
6
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
7
[SID48413683]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
8
[SID48415159]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
9
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
10
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
11
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
12
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
13
[SID48413681]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
14
[SID48413682]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
15
[SID17389585]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
16
[SID103567994]
Anticarcinogenic activity in rat assessed as induction of tumors per day [AID318681, Type: Literature]
View
17
[SID26753101]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
18
[SID144210811]
Potency-Replicate_1 54.4827qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
19
[SID144210811]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
20
[SID144208982]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
21
[SID144208982]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
22
[SID17389585]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
23
[SID17389585]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
24
[SID144210811]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway [AID743222, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
25
[SID144210811]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway [AID743217, Type: confirmatory]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
26
[SID144208982]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
27
[SID144208982]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
28
[SID144210811]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743239, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
29
[SID144210811]
qHTS assay to identify small molecule antagonists of the farnesoid-X-receptor (FXR) signaling pathway: Summary [AID743240, Type: summary]farnesoid X nuclear receptor [Homo sapiens] [gi:325495553]
View
30
[SID26753101]
Potency-Replicate_1 qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
View
31
[SID17389585]
Potency-Replicate_1 qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
View
32
[SID17389585]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
View
33
[SID144210811]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway [AID743212, Type: confirmatory]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
34
[SID144210811]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743226, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
35
[SID144210811]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway: Summary [AID743227, Type: summary]peroxisome proliferator-activated receptor delta [Homo sapiens] [gi:216409690]
View
36
[SID144210811]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
37
[SID144210811]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
38
[SID144210811]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
39
[SID17389585]
Potency qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling [AID588536, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
40
[SID144208982]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
41
[SID144208982]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
42
[SID144208982]
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743199, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
43
[SID26753101]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
44
[SID26753101]
Potency qHTS assay for small molecule agonists of vitamin D receptor signaling [AID588543, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
45
[SID144208982]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743241, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
46
[SID144208982]
qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway: Summary [AID743242, Type: summary]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
47
[SID144208982]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway [AID743222, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
48
[SID26753101]
Potency qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
49
[SID26753101]
Potency qHTS assay for small molecule agonists of estrogen receptor alpha signaling [AID588514, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View
50
[SID17389585]
Potency qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
View