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BioActivity Data for Compound 3-tert-butyl-4-hydroxyanisole (CID 8456)

BioActivity Outcomes:
Active(11)
 
 
Inactive(964)
 
 
Inconclusive(38)
 
 
Unspecified(32)
 
 
Top Targets:
7tm 4(41)
 
 
NR LBD PPAR(27)
 
 
 
NR LBD AR(16)
 
 
 
NR LBD ER(16)
 
 
NR LBD TR(14)
 
 
 
BioAssay Types:
Screening(483)
 
 
 
Confirmatory(415)
 
 
 
 
 
Summary(58)
 
 
 
 
Literature(51)
 
 
 
 
BioAssay Categories:
In vitro(3)
 
 
In vivo(1)
 
 
Biochemical(122)
 
 
Toxicity(28)
 
 
 
 
ADME(5)
 
 
Cell-based(133)
 
 
Organism-base..(13)
 
 
BioActivity Types:
Potency(403)
 
 
 
 
 
IC50(46)
 
 
 
 
EC50(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 827    Data Row: 1045   Total Pages: 53   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210402]
Potency-Replicate_1 24.3365qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144210402]
Ratio Potency (uM) 25.2886qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID103465969]
IC50 28.2Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins [AID1055727, Type: Literature]
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4
[SID144209020]
Potency-Replicate_1 30.7002qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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5
[SID103465969]
IC50 43Antioxidant activity assessed as DPPH free radical scavenging activity [AID375499, Type: Literature]
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6
[SID144209020]
Ratio Potency (uM) 49.098qHTS assay to identify small molecule agonists of the AP-1 signaling pathway: Summary [AID1159528, Type: summary]v-jun sarcoma virus 17 oncogene homolog (avian) [Homo sapiens] [gi:119627033]
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7
[SID26754492]
Potency-Replicate_1 50.1187qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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8
[SID48413346]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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9
[SID48413346]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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10
[SID48413346]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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11
[SID48413346]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
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12
[SID103465969]
IC50 79.16Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins [AID436183, Type: Literature]
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13
[SID103465969]
Antioxidant activity assessed as super oxide scavenging activity after 150 mins by spectrophotometric analysis [AID538400, Type: Literature]
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14
[SID103465969]
Antioxidant activity assessed as DPPH free radical scavenging activity after 30 mins by spectrophotometric analysis [AID538398, Type: Literature]
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15
[SID103465969]
Antioxidant activity assessed as nitric oxide scavenging activity after 150 mins by spectrophotometric analysis [AID538399, Type: Literature]
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16
[SID103465969]
Antioxidant activity assessed as total reducing activity after 30 mins by spectrophotometric analysis [AID538395, Type: Literature]
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17
[SID11532886]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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18
[SID103465969]
Specific activity of expressed human recombinant UGT1A1 [AID624606, Type: Literature]UDP-glucuronosyltransferase 1-1 [gi:136729]
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19
[SID103465969]
Specific activity of expressed human recombinant UGT1A9 [AID624612, Type: Literature]UDP-glucuronosyltransferase 1-9 [gi:29839451]
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20
[SID103465969]
Specific activity of expressed human recombinant UGT1A6 [AID624609, Type: Literature]UDP-glucuronosyltransferase 1-6 [gi:29840832]
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