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2,4-dichlorophenol (CID 8449) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(362)
 
 
Inconclusive(16)
 
 
Unspecified(11)
 
 
Top Targets:
NR LBD PPAR(26)
 
 
 
NR LBD AR(18)
 
 
NR LBD ER(18)
 
 
NR LBD TR(14)
 
 
NR LBD GR(12)
 
 
BioAssay Types:
Confirmatory(305)
 
 
 
 
Summary(48)
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(305)
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 256    Data Row: 394   Total Pages: 20   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210360]
Potency-Replicate_1 27.306qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144210360]
Ratio Potency (uM) 28.3743qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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3
[SID144208787]
Potency-Replicate_1 30.3888qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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4
[SID144208787]
Ratio Potency (uM) 42.9253qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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5
[SID48415158]
DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
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6
[SID103329897]
IC50 242Inhibitory activity on germination of Bacillus subtilis PCI219 spores was determined. [AID40623, Type: Literature]
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7
[SID103329897]
Inhibition of Bacillus subtilis PCI219 spore germination, expressed as log 1/I50 [AID40936, Type: Literature]
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8
[SID103329897]
Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA [AID288184, Type: Literature]
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9
[SID103329897]
Permeability coefficient through artificial membrane in presence of stirred water layer [AID288185, Type: Literature]
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10
[SID103329897]
Membrane retention in permeability experiment with artificial membrane [AID288191, Type: Literature]
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11
[SID103329897]
Partition coefficient, log P of the compound [AID288192, Type: Literature]
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12
[SID17389929]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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13
[SID26752956]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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14
[SID103329897]
Dissociation constant (pKa) [AID25611, Type: Literature]
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15
[SID103329897]
Partition coefficient (logD7.2) [AID26261, Type: Literature]
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16
[SID103329897]
Partition coefficient (logP) [AID26793, Type: Literature]
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17
[SID17389929]
Potency 15.8489qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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18
[SID144208787]
Potency-Replicate_1 30.6614qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743075, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144208787]
Potency-Replicate_1 48.595qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID144210360]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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