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D-Aspartic Acid (CID 83887) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(322)
 
 
Inconclusive(21)
 
 
Unspecified(6)
 
 
Top Targets:
p450(14)
 
 
PLDc mTdp1 2(9)
 
 
 
NR LBD TR(9)
 
 
Tubulin-bindi..(8)
 
 
 
NR LBD GR(8)
 
 
 
BioAssay Types:
Confirmatory(255)
 
 
 
 
Literature(69)
 
 
 
 
Summary(15)
 
 
 
Screening(3)
 
 
BioActivity Types:
Potency(220)
 
 
 
 
EC50(3)
 
 
Kd(2)
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 190    Data Row: 355   Total Pages: 18   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103199585]
Kd 0.009Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter [AID328866, Type: Literature]
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2
[SID103199585]
Kd 0.01Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter L130W mutant fluorescence-based assay in presence of NaCl [AID328865, Type: Literature]
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3
[SID11110794]
Potency 7.9433qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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4
[SID103199585]
IC50 10Displacement of [3H]CPP from N-methyl-D-aspartate glutamate receptor in rat brain membrane [AID144456, Type: Literature]
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5
[SID11110794]
qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region [AID589, Type: other]
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6
[SID11110794]
qHTS Assay for Spectroscopic Profiling in A350 Spectral Region [AID590, Type: other]
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7
[SID103199585]
EC50 1000Agonistic activity at mGlu6 receptor expressed in CHO cells [AID107251, Type: Literature]
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8
[SID103199585]
EC50 1000Agonistic activity at mGlu1-alpha receptor expressed in CHO cells [AID108645, Type: Literature]
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9
[SID103199585]
EC50 1000Agonistic activity at mGlu2 receptor expressed in CHO cells [AID109003, Type: Literature]
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10
[SID103199585]
Comparative inhibition of L-Glutamate uptake at the concentration of 5 uM of [3H]-L- glutamate radioligand [AID174973, Type: Literature]
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11
[SID11113408]
Cytochrome panel assay with activity outcomes [AID1851, Type: other]
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12
[SID26751646]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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13
[SID11113408]
Potency 0.1585qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) [AID2517, Type: confirmatory]Chain A, Human Ape1 Endonuclease With Bound Abasic Dna And Mn2+ Ion [gi:6980812]
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14
[SID144204455]
Potency-Replicate_1 33.4915qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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15
[SID144204455]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the thyroid receptor (TR) signaling pathway [AID743066, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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16
[SID144204455]
TR Potency (uM) qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway: Summary [AID743067, Type: summary]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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17
[SID144204455]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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18
[SID144204455]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743080, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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19
[SID144204455]
ER Potency (uM) qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line: Summary [AID743091, Type: summary]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID11113408]
Potency qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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