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BioActivity Data for Compound 3,4-dihydroxyphenylethanol (CID 82755)

BioActivity Outcomes:
Active(3)
 
 
Inactive(3)
 
 
Unspecified(4)
 
 
BioAssay Types:
Literature(10)
 
 
 
 
BioAssay Categories:
Biochemical(2)
 
 
Toxicity(1)
 
 
ADME(1)
 
 
Cell-based(6)
 
 
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 10    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136938848]
IC50 17.53Antiviral activity against Influenza A virus (A/Vietnam/1194/2004(H5N1)) infected in MDCK cells assessed as inhibition of viral replication after 2 to 3 days by crystal violet staining-based plaque reduction assay [AID1152622, Type: Literature]
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2
[SID136938848]
Antiviral activity against Influenza A virus (A/Vietnam/1194/2004(H5N1)) infected in MDCK cells assessed as inhibition of viral production at 30 uM pretreated for 2 to 4 hrs followed by compound washout and viral infection measured after 2 hrs by crystal violet staining-based plaque reduction assay [AID1152626, Type: Literature]
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3
[SID136938848]
Antiviral activity against Influenza A virus (A/Vietnam/1194/2004(H5N1)) infected in MDCK cells assessed as inhibition of viral production at 30 uM treated simultaneously with viral infection measured after 2 hrs by crystal violet staining-based plaque reduction assay relative to control [AID1152627, Type: Literature]
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4
[SID136938848]
CC50 172.11Cytotoxicity against MDCK cells after 72 hrs by MTT assay [AID1152623, Type: Literature]
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5
[SID136938848]
Selectivity index, ratio of CC50 for MDCK cells to IC50 for Influenza A virus (A/Vietnam/1194/2004(H5N1)) [AID1152624, Type: Literature]
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6
[SID136938848]
Antiviral activity against Influenza A virus (A/Vietnam/1194/2004(H5N1)) infected in MDCK cells assessed as inhibition of viral production at 30 uM treated 2 hrs post viral infection measured after 2 hrs by crystal violet staining-based plaque reduction assay [AID1152628, Type: Literature]
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7
[SID136938848]
Octanol-water partition coefficient, log Kow of the compound by HPLC analysis [AID646698, Type: Literature]
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8
[SID136938848]
Antiviral activity against Influenza A virus (A/Vietnam/1194/2004(H5N1)) infected in MDCK cells assessed as inhibition of viral production at 30 uM treated 4 to 8 hrs post viral infection measured after 2 hrs by crystal violet staining-based plaque reduction assay [AID1152629, Type: Literature]
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9
[SID136938848]
Inhibition of Influenza A virus H5N1 hemagglutinin adsorption to chicken RBC at 100 ug/ml by two-fold dilution method [AID1152630, Type: Literature]
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10
[SID136938848]
Inhibition of Influenza A virus H5N1 neuraminidase up to 20 ug/ml by fluorescence spectrophotometric analysis [AID1152625, Type: Literature]
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