Dicofol (CID 8268) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(5)
 
 
Inactive(150)
 
 
Inconclusive(34)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD PPAR(10)
 
 
 
NR LBD TR(8)
 
 
 
P53(4)
 
 
 
NR LBD VDR(4)
 
 
NR LBD RXR li..(4)
 
 
 
BioAssay Types:
Confirmatory(167)
 
 
 
 
Literature(5)
 
 
 
BioActivity Types:
Potency(131)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 152    Data Row: 195   Total Pages: 4   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389924]
Potency 39.8107qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
2
[SID17389924]
Potency 39.8107qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
3
[SID17389924]
Potency 39.8107qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
4
[SID17389924]
Potency 39.8107qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
5
[SID17389924]
Potency 39.8107qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]KCNH2 gene product [Homo sapiens] [gi:325651834]
View
6
[SID17389924]
 Cell Viability - N2a [AID540, Type: confirmatory]
View
7
[SID48415143]
 DSSTox (EPAFHM) EPA Fathead Minnow Acute Toxicity [AID1188, Type: other]
View
8
[SID48413595]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
9
[SID48413595]
 DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
10
[SID26752900]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
11
[SID103520034]
 Octanol-water partition coefficient, log KOW of the compound [AID289345, Type: Literature]
View
12
[SID103520034]
 Octanol-air partition coefficient, log KOA of the compound [AID289346, Type: Literature]
View
13
[SID103520034]
 Biomagnification factors in Diporeia [AID289347, Type: Literature]
View
14
[SID103520034]
 Biomagnification factors in human [AID289348, Type: Literature]
View
15
[SID17389924]
 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
View
16
[SID17389924]
Potency 0.0794qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
17
[SID17389924]
Potency 0.0794qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
18
[SID17389924]
Potency 0.0794qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
View
19
[SID17389924]
Potency 31.6228qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
20
[SID17389924]
Potency 31.6228qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
21
[SID17389924]
Potency 31.6228qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay [AID995, Type: confirmatory]mitogen-activated protein kinase 1 [Homo sapiens] [gi:66932916]
View
22
[SID17389924]
 qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
View
23
[SID17389924]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
24
[SID17389924]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
25
[SID17389924]
Potency qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling [AID588546, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
26
[SID17389924]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
27
[SID17389924]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
28
[SID17389924]
Potency qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
View
29
[SID17389924]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
30
[SID17389924]
Potency qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
31
[SID26752900]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
32
[SID26752900]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
33
[SID26752900]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
34
[SID26752900]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
35
[SID26752900]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
36
[SID26752900]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
37
[SID17389924]
Potency qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
38
[SID17389924]
Potency qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
39
[SID17389924]
Potency qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling [AID588545, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
40
[SID17389924]
Potency qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling [AID588547, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
41
[SID17389924]
Potency qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling [AID588547, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
42
[SID17389924]
Potency qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling [AID588547, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
43
[SID17389924]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
44
[SID17389924]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
45
[SID17389924]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
46
[SID17389924]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
47
[SID17389924]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
48
[SID17389924]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
View
49
[SID26752900]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View
50
[SID26752900]
Potency qHTS assay for small molecule antagonists of vitamin D receptor signaling [AID588541, Type: confirmatory]vitamin D (1,25- dihydroxyvitamin D3) receptor [Homo sapiens] [gi:216409708]
View