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(2'-(4-aminophenyl)-(2,5'-bi-1H-benzimidazol)-5-amine) (CID 824226) - Compound BioActivity Data
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BioActivity Outcomes:
Active(74)
 
 
Inactive(181)
 
 
Inconclusive(50)
 
 
Unspecified(4)
 
 
Top Targets:
HELICc(10)
 
 
GH27(8)
 
 
 
7tm 4(8)
 
 
 
Bromo ALL-1(7)
 
 
 
Pyr redox dim(7)
 
 
BioAssay Types:
Confirmatory(266)
 
 
 
 
 
Screening(24)
 
 
 
Literature(17)
 
 
 
 
Summary(1)
 
 
BioActivity Types:
Potency(264)
 
 
 
 
 
IC50(8)
 
 
 
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 213    Data Row: 309   Total Pages: 16   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103712730]
IC50 0.00022Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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2
[SID103712730]
IC50 0.00028Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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3
[SID103712730]
IC50 0.00052Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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4
[SID103712730]
IC50 0.00074Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay [AID524792, Type: Literature]
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5
[SID103712730]
IC50 0.00074Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay [AID524794, Type: Literature]
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6
[SID103712730]
IC50 0.00083Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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7
[SID103712730]
IC50 0.001Antiplasmodial activity against Plasmodium falciparum Dd2 after 72 hrs by SYBR green assay [AID524793, Type: Literature]
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8
[SID103712730]
EC50 0.0556NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay [AID449704, Type: Literature]
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9
[SID26753597]
Potency 0.0631qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4 [AID884, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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10
[SID103712730]
EC50 0.1196NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay [AID449703, Type: Literature]
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11
[SID26753597]
Potency 0.2512qHTS for differential inhibitors of proliferation of Plasmodium falciparum line W2 [AID1883, Type: confirmatory]
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12
[SID26753597]
Potency 0.2617Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID488745, Type: confirmatory]
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13
[SID26753597]
Potency 0.3548qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 3D7 [AID1876, Type: confirmatory]
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14
[SID26753597]
Potency 0.4147Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID488752, Type: confirmatory]
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15
[SID26753597]
Potency 0.7079qHTS for differential inhibitors of proliferation of Plasmodium falciparum line D10 [AID1877, Type: confirmatory]
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16
[SID26753597]
Potency 0.7943qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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17
[SID26753597]
Potency 0.7943qHTS for differential inhibitors of proliferation of Plasmodium falciparum line HB3 [AID1886, Type: confirmatory]
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18
[SID26753597]
Potency 0.8913qHTS for differential inhibitors of proliferation of Plasmodium falciparum line GB4 [AID1816, Type: confirmatory]
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19
[SID26753597]
Potency 1qHTS for differential inhibitors of proliferation of Plasmodium falciparum line Dd2 [AID1882, Type: confirmatory]
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20
[SID26753597]
Potency 1.122qHTS Assay for Identification of Small Molecule Antagonists for NFkB Signaling Pathway [AID895, Type: confirmatory]NFKB1 protein, partial [Homo sapiens] [gi:21620132]
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