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1-UNDECANOL (CID 8184) - Compound BioActivity Data
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BioActivity Outcomes:
Active(15)
 
 
Inactive(177)
 
 
Inconclusive(27)
 
 
Unspecified(10)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD AR(16)
 
 
 
NR LBD ER(16)
 
 
NR LBD Fxr(10)
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(155)
 
 
 
 
Summary(48)
 
 
 
Literature(9)
 
 
 
BioActivity Types:
Potency(191)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 135    Data Row: 229   Total Pages: 12   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID144210866]
Potency-Replicate_1 21.6899qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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2
[SID144210866]
Potency-Replicate_1 27.306qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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3
[SID144210866]
Potency-Replicate_1 27.306qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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4
[SID144210866]
Potency-Replicate_1 27.306qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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5
[SID144210866]
Potency-Replicate_1 30.6379qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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6
[SID144210866]
Potency-Replicate_1 43.6412qHTS assay for small molecule activators of the heat shock response signaling pathway - cell viability counter screen [AID743209, Type: confirmatory]
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7
[SID144210866]
Potency-Replicate_1 43.6412qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
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8
[SID144210866]
Potency-Replicate_1 48.5577qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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9
[SID144210866]
Potency-Replicate_1 48.9662qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
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10
[SID144210866]
Potency-Replicate_1 54.4827qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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11
[SID144210866]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway - cell viability counter screen [AID743203, Type: confirmatory]
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12
[SID144210866]
Potency-Replicate_1 61.1306qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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13
[SID144210866]
Potency-Replicate_1 61.1306qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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14
[SID103194221]
Effect on nitric oxide production in mouse RAW264.7 cells assessed as nitrite level at 1 uM after 24 hrs by Griess reagent assay [AID362061, Type: Literature]
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15
[SID103194221]
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite level at 1 uM administered 1 hr before LPS challenge and measured after 24 hrs by Griess reagent assay [AID362059, Type: Literature]
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16
[SID103194221]
Cytotoxicity against mouse RAW264.7 cells assessed as survival at 1 uM after 24 hrs by MTT assay [AID362060, Type: Literature]
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17
[SID103194221]
Minimum inhibitory concentration against Propionibacterium acnes was determined [AID160385, Type: other]
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18
[SID103194221]
Minimum inhibitory concentration against Staphylococcus aureus was determined [AID205701, Type: other]
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19
[SID103194221]
Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method [AID332912, Type: Literature]
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20
[SID26757441]
qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against a panel of isogenic chicken DT40 cell lines with known DNA damage response pathways [AID651838, Type: other]
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