piperidine (CID 8082) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(3)
 
 
Unspecified(9)
 
 
Top Targets:
p450(1)
 
 
BioAssay Types:
Literature(10)
 
 
 
BioActivity Types:
Kd(2)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 13    Data Row: 13   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103178965]
Kd 0.12Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at binding site 2 [AID30389, Type: Literature]
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2
[SID103178965]
Kd 69Ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at binding site 3. [AID30391, Type: Literature]
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3
[SID103178965]
Ki 54000Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting [AID630741, Type: Literature]
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4
[SID103178965]
Inhibition of Thromboxane synthetase at 100 uM [AID213129, Type: Literature]Thromboxane-A synthase [gi:254763392]
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5
[SID103178965]
Compounds was evaluated for their ability to enhance (+/-)-[3H]nicotine binding at a dose range 10 E -9 - 10 E -6 M was reported [AID30528, Type: Literature]
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6
[SID103178965]
Dissociation constant, pKa of the compound [AID342464, Type: Literature]
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7
[SID103178965]
Association constant was determined [AID25336, Type: Literature]
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8
[SID103178965]
Maximum percent of enhancement of binding. [AID30377, Type: Literature]
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9
[SID103178965]
Maximum percent of inhibition of binding was determined [AID30378, Type: Literature]
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10
[SID103178965]
Compound was evaluated for ability to enhance the binding of (+/-)-[3H]nicotine to the rat brain P2 fraction at binding site 1; 10e-9-10e-6 [AID30386, Type: Literature]
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11
[SID48414344]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
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12
[SID48414344]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
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13
[SID48414344]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
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