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AP-263/40917498 (CID 801592) - Compound BioActivity Data
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BioActivity Outcomes:
Active(29)
 
 
Inactive(800)
 
 
Inconclusive(29)
 
 
Unspecified(2)
 
 
Top Targets:
7tm 4(48)
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(11)
 
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(570)
 
 
 
 
Confirmatory(261)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(168)
 
 
 
 
 
IC50(50)
 
 
 
 
EC50(15)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 788    Data Row: 860   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7966893]
Potency 2.5929qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID7966893]
AbsAC40_uM 2.65Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Inhibitor_Dose_CherryPick_Activity [AID652053, Type: confirmatory]
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3
[SID7966893]
EC50 3.47Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) [AID430, Type: confirmatory]
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4
[SID7966893]
Potency 4.1095qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID7966893]
EC50 4.11Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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6
[SID160657846]
AbsAC40_uM 4.6Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Inhibitor_Dose_DryPowder_Activity [AID687040, Type: confirmatory]
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7
[SID7966893]
Potency 5.1735A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID7966893]
EC50 9.116Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells [AID1988, Type: confirmatory]
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9
[SID7966893]
Potency 9.2qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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10
[SID7966893]
EC50_1 52.3Inhibitors of T-Type Calcium Channel [AID489005, Type: confirmatory]voltage-dependent T-type calcium channel subunit alpha-1H isoform a [Homo sapiens] [gi:53832009]
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11
[SID188376402]
Confirmed inhibitors of the Cav3 T-type Calcium Channel [AID1053190, Type: other]voltage-dependent T-type calcium channel subunit alpha-1H isoform a [Homo sapiens] [gi:53832009]
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12
[SID7966893]
Inhibitors of Cav3 T-type Calcium Channels: Primary Screen [AID449739, Type: screening]voltage-dependent T-type calcium channel subunit alpha-1H isoform a [Homo sapiens] [gi:53832009]
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13
[SID7966893]
HCS assay for microtubule stabilizers [AID2205, Type: screening]tubulin beta chain isoform b [Homo sapiens] [gi:29788785]
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14
[SID7966893]
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) [AID695, Type: confirmatory]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
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15
[SID7966893]
Cell Proliferation & Viability (Cytotoxicity) Primary Assay 60K MLSMR [AID463, Type: screening]
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16
[SID7966893]
Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen [AID598, Type: screening]
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17
[SID7966893]
Counterscreen for inhibitors of mutant JAK2V617F: Cell-based high throughput screening assay for inhibitors of parental Ba/F3 cell viability. [AID1520, Type: screening]
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18
[SID7966893]
Cell signaling CRE-BLA (Fsk stim) [AID662, Type: confirmatory]
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19
[SID7966893]
MLPCN Alpha-Synuclein 5'UTR - 5'-UTR binding - inhibitors [AID1813, Type: screening]
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20
[SID7966893]
Small molecule inhibitors of miR122 Measured in Cell-Based System Using Plate Reader - 2144-01_Inhibitor_SinglePoint_HTS_Activity [AID602342, Type: screening]
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