Bookmark and Share
indole (CID 798) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(16)
 
 
Inactive(352)
 
 
Inconclusive(12)
 
 
Unspecified(34)
 
 
Top Targets:
NR LBD PPAR(24)
 
 
 
NR LBD ER(21)
 
 
NR LBD AR(21)
 
 
 
NR LBD VDR(13)
 
 
NR LBD GR(12)
 
 
 
BioAssay Types:
Confirmatory(221)
 
 
 
 
 
Literature(111)
 
 
 
 
Summary(72)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(273)
 
 
 
 
Kd(7)
 
 
Ki(5)
 
 
IC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 177    Data Row: 414   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179045]
IC50 1.78Cytotoxicity against human SK-N-SH cells after 48 hrs by MTT assay [AID652686, Type: Literature]
View
2
[SID103179045]
Ki 2.33Inhibition of human carbonic anhydrase 4 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644086, Type: Literature]Carbonic anhydrase 4 [gi:115465]
View
3
[SID103179045]
Ki 3.63Inhibition of human carbonic anhydrase 6 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644087, Type: Literature]Carbonic anhydrase 6 [gi:116241278]
View
4
[SID103179045]
IC50 15.58Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay [AID652688, Type: Literature]
View
5
[SID103179045]
Ki 17.6Inhibition of bovine carbonic anhydrase 3 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644088, Type: Literature]Carbonic anhydrase 3 [gi:118572923]
View
6
[SID144213254]
AhR Potency (uM) 22.5385qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
7
[SID144213254]
Potency-Replicate_1 27.306qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
8
[SID103179045]
Ki 27.4Inhibition of human carbonic anhydrase 1 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644084, Type: Literature]Carbonic anhydrase 1 [gi:115449]
View
9
[SID144208875]
AhR Potency (uM) 27.9132qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway: Summary [AID743122, Type: summary]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
10
[SID144208875]
Potency-Replicate_1 30.14qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
11
[SID103179045]
Ki 32.5Inhibition of human carbonic anhydrase 2 using 4-nitrophenylacetate as substrate after 3 mins using spectrophotometry by Lineweaver-Burk plot analysis [AID644085, Type: Literature]Carbonic anhydrase 2 [gi:115456]
View
12
[SID103179045]
Binding affinity to amyloid beta (1 to 42) oligomers by fluorescence quenching after 30 mins [AID475507, Type: Literature]
View
13
[SID103179045]
Binding affinity to amyloid beta (1 to 42) fibrils by change in fluorescence at 100 uM after 10 mins [AID475504, Type: Literature]
View
14
[SID103179045]
Binding affinity to amyloid beta (1 to 42) oligomers by change in fluorescence at 100 uM after 10 mins [AID475505, Type: Literature]
View
15
[SID144206089]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
View
16
[SID144206089]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
View
17
[SID103179045]
IC50 100Cytotoxicity against human A549 cells after 48 hrs by MTT assay [AID652687, Type: Literature]
View
18
[SID103179045]
IC50 100Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay [AID652685, Type: Literature]
View
19
[SID103179045]
Kd 290Dissociation constant against T4 lysozyme mutant L99A [AID238119, Type: Literature]Lysozyme [gi:126605]
View
20
[SID103179045]
Kd 300Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1 [AID99593, Type: Literature]Intercellular adhesion molecule 1 [gi:68067956]
View