Bookmark and Share
imidazole (CID 795) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(1)
 
 
Inactive(332)
 
 
Inconclusive(8)
 
 
Unspecified(24)
 
 
Top Targets:
NR LBD PPAR(21)
 
 
 
NR LBD ER(16)
 
 
NR LBD AR(16)
 
 
 
NR LBD TR(10)
 
 
NR LBD Fxr(10)
 
 
BioAssay Types:
Confirmatory(274)
 
 
 
Summary(48)
 
 
 
Literature(27)
 
 
 
 
BioActivity Types:
Potency(274)
 
 
 
IC50(7)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 266    Data Row: 365   Total Pages: 19   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103176105]
IC50 40Inhibition of purified mouse inducible nitric oxide synthase catalyzed [14C]L-citrulline production at a compound concentration of 1 mM in presence of 50 uM L-arginine [AID147271, Type: Literature]
View
2
[SID103176105]
Ki 175Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrulline [AID404423, Type: Literature]
View
3
[SID103176105]
IC50 368Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 by LDH assay [AID497160, Type: Literature]
View
4
[SID103176105]
IC50 670Inhibitory activity against thromboxane A2 synthetase [AID212779, Type: Literature]
View
5
[SID103176105]
IC50 3675Cytotoxicity against CHO cells after 48 hrs by MTT assay [AID497161, Type: Literature]
View
6
[SID103176105]
IC50 4000Inhibition of porcine aorta prostacyclin PGI-2 synthase [AID155525, Type: Literature]
View
7
[SID103176105]
IC50 10000Inhibition of ram seminal vesicle Cyclooxygenase [AID161184, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
View
8
[SID103176105]
IC50 10000Inhibition of ram seminal vesicle Cyclooxygenase [AID161184, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
View
9
[SID103176105]
Antifungal activity against yeast AD1-8u expressing Candida albicans CaMdr1p by agar disk diffusion assay [AID537734, Type: Literature]
View
10
[SID103176105]
Maximum enhancement of styrene oxide hydrolase activity was reported at compound concentration of 1e-1M [AID208350, Type: Literature]
View
11
[SID103176105]
The pKa value was measured at N15 chemical shift changes due to protonation [AID233501, Type: Literature]
View
12
[SID103176105]
Ionization constant (pKa) [AID25092, Type: Literature]
View
13
[SID103176105]
Dissociation constant was evaluated [AID25595, Type: Literature]
View
14
[SID103176105]
pKa value by 1H NMR spectroscopy [AID26364, Type: other]
View
15
[SID103176105]
Dissociation constant (pKa, calculated using GNN method) [AID26397, Type: Literature]
View
16
[SID103176105]
Partition coefficient (logP) [AID26810, Type: Literature]
View
17
[SID103176105]
Selectivity ratio of IC50 for Plasmodium falciparum to IC50 for CHO cells [AID497162, Type: Literature]
View
18
[SID103176105]
Enhanced styrene oxide hydrolase activity pH 8.7 [AID208343, Type: Literature]Epoxide hydrolase 1 [gi:123928]
View
19
[SID103176105]
Enhancement of epoxide hydrolase activity [AID70214, Type: Literature]Epoxide hydrolase 1 [gi:123928]
View
20
[SID103176105]
Antifungal activity against yeast AD1-8u expressing Candida albicans CaCdr1p by agar disk diffusion assay [AID537736, Type: Literature]
View